glycoprotein C/gC 蛋白, HHV-2 (Cell-Free, His)

Glycoprotein C (gC protein) is an important attachment protein that promotes virus binding to the cell surface by interacting with heparan sulfate or chondroitin sulfate. This critical role emphasizes its importance during the initial stages of viral infection. glycoprotein C/gC Protein, HHV-2 (Cell-Free, His) is the recombinant Virus-derived glycoprotein C/gC protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of glycoprotein C/gC Protein, HHV-2 (Cell-Free, His) is 453 a.a., with molecular weight of 50.5 kDa.

糖蛋白 C（gC 蛋白）作为一种重要的附着蛋白出现，通过与硫酸乙酰肝素或硫酸软骨素的相互作用促进病毒与细胞表面的结合。这一关键作用强调了其在病毒感染初始阶段的重要性。除了其附着功能外，gC 蛋白还通过抑制宿主补体级联的激活在免疫逃避中发挥重要作用。它与宿主补体成分 C3b 相互作用，导致补体级联的调节，破坏宿主免疫反应。这种双重功能使 gC 蛋白成为病毒进入过程和病毒逃避宿主免疫系统的关键角色。

Virus

E. coli Cell-free

N-10*His

Q89730 (S28-R480)

1487331

SPGRTITVGPRGNASNAAPSASPRNASAPRTTPTPPQPRKATKSKASTAKPAPPPKTGPPKTSSEPVRCNRHDPLARYGSRVQIRCRFPNSTRTEFRLQIWRYATATDAEIGTAPSLEEVMVNVSAPPGGQLVYDSAPNRTDPHVIWAEGAGPGASPRLYSVVGPLGRQRLIIEELTLETQGMYYWVWGRTDRPSAYGTWVRVRVFRPPSLTIHPHAVLEGQPFKATCTAATYYPGNRAEFVWFEDGRRVFDPAQIHTQTQENPDGFSTVSTVTSAAVGGQGPPRTFTCQLTWHRDSVSFSRRNASGTASVLPRPTITMEFTGDHAVCTAGCVPEGVTFAWFLGDDSSPAEKVAVASQTSCGRPGTATIRSTLPVSYEQTEYICRLAGYPDGIPVLEHHGSHQPPPRDPTERQVIRAVEGAGIGVAVLVAVVLAGTAVVYLTHASSVRYRRLR

50.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.