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  4. Hemopexin 蛋白, Rat (His)

Hemopexin 蛋白, Rat (His)

目录号: HY-P72236
产品使用指南

血红素结合蛋白具有血红素结合能力，可充当转运蛋白，促进血红素转运至肝脏。在肝脏中，血红素被分解，回收的铁被利用。然后释放的血红素结合蛋白返回循环，强调其在有效管理体内血红素和铁代谢方面的重要作用。Hemopexin 蛋白, Rat (His) 是重组的 血红素结合蛋白，由 E. coli 表达，带有 N-6*His 标签。Hemopexin 蛋白, Rat (His) 全长 437 个氨基酸，分子量约为 ~52.9 kDa。

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规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

Hemopexin Protein, with its heme-binding ability, acts as a transporter, facilitating heme transport to the liver. In the liver, heme is broken down, and the recovered iron is utilized. The liberated hemopexin protein then returns to circulation, underscoring its vital role in efficiently managing heme and iron metabolism in the body. Hemopexin Protein, Rat (His) is the recombinant rat-derived Hemopexin protein, expressed by E. coli , with N-6*His labeled tag. The total length of Hemopexin Protein, Rat (His) is 437 a.a., with molecular weight of ~52.9 kDa.
研究背景

血红素结合蛋白具有与血红素结合的能力，作为转运蛋白促进其转运至肝脏。一旦进入肝脏，血红素就会被分解，铁会被回收。随后，不含血红素的血红素结合蛋白返回循环。这一机制凸显了血红素结合蛋白在体内血红素和铁代谢的有效管理中的关键作用。
种属

Rat
表达系统

E. coli
标签

N-6*His
蛋白编号

P20059 (N24-Q460)
基因 ID

58917  [NCBI]
蛋白结构
N-term
6*His
Hemopexin (N24-Q460)
Accession # P20059
C-term
同用名
Hpx; Hemopexin
氨基酸序列

NPLPAAHETVAKGENGTKPDSDVIEHCSDAWSFDATTMDHNGTMLFFKGEFVWRGHSGIRELISERWKNPVTSVDAAFRGPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWPAVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFISCPGRGHGKLRNGTAHGNSTHPMHSRCNADPGLSALLSDHRGATYAFSGSHYWRLDSSRDGWHSWPIAHHWPQGPSAVDAAFSWDEKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLDTIDAAFSCPGSSKLYVTSGRRLWWLDLKSGAQATWAELSWPHEKVDGALCLEKSLGPYSCSSNGPNLFFIHGPNLYCYSSIDKLNAAKSLPQPQKVNSILGCSQ

分子量

Approximately 52.9 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Hemopexin Protein, Rat (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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