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  3. HLA-C 蛋白, Human (His)

HLA-C 蛋白, Human (His)

目录号: HY-P71700
COA 产品使用指南

HLA-C 蛋白是 MHC I 类家族的一部分,对于免疫系统功能至关重要,可将抗原呈递给细胞毒性 T 细胞。在这个家族中,HLA-C 参与调节免疫反应和识别外来物质。需要进一步探索以揭示更广泛的 MHC I 类家族中的特定功能和影响,强调其在免疫监视和宿主防御机制中的重要性。HLA-C 蛋白, Human (His) 是重组的 HLA-C 蛋白,由 E. coli 表达,带有 N-6*His 标签。HLA-C 蛋白, Human (His) 全长 284 个氨基酸,分子量约为 ~36.7 kDa。

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规格 价格 是否有货 数量
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5 μg ¥630 In-stock
10 μg ¥1070 In-stock
50 μg ¥3000 In-stock
100 μg   询价  

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描述

HLA-C Protein, part of the MHC class I family, is crucial for immune system functions, presenting antigens to cytotoxic T cells. In this family, HLA-C is involved in regulating immune responses and recognizing foreign substances. Further exploration is needed to reveal specific functions and implications within the broader MHC class I family, emphasizing its significance in immune surveillance and host defense mechanisms. HLA-C Protein, Human (His) is the recombinant human-derived HLA-C protein, expressed by E. coli , with N-6*His labeled tag. The total length of HLA-C Protein, Human (His) is 284 a.a., with molecular weight of ~36.7 kDa.

研究背景

HLA-C 蛋白是主要组织相容性复合体 (MHC) I 类家族的成员,它属于一组通过向细胞毒性 T 细胞呈递抗原而在免疫系统中发挥关键作用的蛋白质。作为 MHC I 类家族的一部分,HLA-C 参与免疫反应的调节和外来物质的识别。有必要进一步探索,以揭示 HLA-C 在 MHC I 类家族更广泛的背景下的具体功能和影响,阐明其在免疫监视和宿主防御机制中的重要性。

种属

Human

表达系统

E. coli

标签

N-6*His

蛋白编号

O78179 (C25-I308)

基因 ID

/

蛋白结构
N-term
6*His
HLA-C (C25-I308)
Accession # O78179
C-term
同用名
HLA class I histocompatibility antigen, C alpha chain; HLA-C protein; MHC class I antigen; HLA-Cw
氨基酸序列

CSHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQTDRVSLRNLRGYYNQSEAGSHTLQWMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARAAEQQRAYLEGTCVEWLRRYLENGKETLQRAEHPKTHVTHHLVSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTIPI

分子量

Approximately 36.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

HLA-C Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
HLA-C Protein, Human (His)
目录号:
HY-P71700
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