Insulin-1/Ins1 蛋白, Mouse (P.pastoris, Myc, His)

Insulin-1 is an important regulator of glucose and can effectively lower blood sugar by increasing cellular permeability to simple sugars, amino acids, and fatty acids. Its effects include accelerating glycolysis, promoting pentose phosphate cycle, and promoting hepatic glycogen synthesis. Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His) is the recombinant mouse-derived Insulin-1/Ins1 protein, expressed by P. pastoris , with C-Myc, N-6*His labeled tag. The total length of Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His) is 84 a.a., with molecular weight (affected by relative charge) of 29 KDa.

胰岛素-1 是血糖调节的关键角色，通过增强细胞对单糖、氨基酸和脂肪酸的通透性，有效降低血糖水平。其多方面作用包括加速糖酵解、促进磷酸戊糖循环以及促进肝脏中糖原的合成。在结构上，Insulin-1 以异二聚体形式存在，包含 B 链和 A 链，通过两个二硫键错综复杂地连接。这些结构特征强调了其在协调维持葡萄糖稳态所必需的代谢过程中的关键作用。

Mouse

P. pastoris

C-Myc;N-6*His

P01325 (F25-N108)

16333  [NCBI]

FVKQHLCGPHLVEALYLVCGERGFFYTPKSRREVEDPQVEQLELGGSPGDLQTLALEVARQKRGIVDQCCTSICSLYQLENYCN

29 kDa.The reducing (R) protein migrat es as 62 kDa in SDS-PAGE may be due to relative charge.

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.