1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. Neuropoietin
  5. Neuropoietin 蛋白, Mouse

神经原素是一种与血小板计数升高和脾肿大相关的蛋白质,参与神经元前体的发育和成熟。通过与 CNTF 受体复合物(包括 CNTF α 链、LIFR 和 IL6ST)结合,神经生成素可能影响与细胞分化相关的信号通路。Neuropoietin 蛋白, Mouse 是重组的 神经生成素蛋白,由 E. coli 表达,不带标签。

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描述

Neurogenin, a protein associated with elevated platelet counts and splenomegaly, is involved in neuronal precursor development and maturation. By binding to the CNTF receptor complex (including CNTF alpha chain, LIFR and IL6ST), neurogenin may affect signaling pathways related to cell differentiation. Neuropoietin Protein, Mouse is the recombinant mouse-derived Neuropoietin protein, expressed by E. coli , with tag free.

研究背景

神经生成素是一种与血小板计数增加和脾肿大相关的蛋白质,可能在神经元前体发育和成熟中发挥至关重要的作用。它通过与三方 CNTF 受体复合物结合发挥作用,该复合物包含 CNTF α 链、LIFR 和 IL6ST。体外观察到的这种相互作用表明神经生成素参与与细胞分化和成熟过程相关的信号通路。该蛋白质在血小板调节和神经发育中的双重作用强调了其在不同生理环境中的多功能性和潜在意义。

种属

Mouse

表达系统

E. coli

标签

Tag Free

蛋白编号

P83714 (A23-A204)

基因 ID

244218  [NCBI]

蛋白结构
N-term
Neuropoietin (A23-A204)
Accession # P83714
C-term
蛋白长度

Full Length of Mature Protein

中文名
Neuropoietin 蛋白
同用名
Cardiotrophin-2; Ctf2; CT-2; Neuropoietin; Np; Gm494
预测分子量
19.7 kDa
分子量

Approximately 20 kDa, based on SDS-PAGE under reducing conditions.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Neuropoietin Protein, Mouse 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
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