RAB27B 蛋白, Human (HEK293)

RAB27B is a dynamic small GTPase that regulates the late endocytic pathway by cycling between its active GTP-bound and inactive GDP-bound states. In the active state, RAB27B interacts with multiple effectors to coordinate endosomal localization, maturation, and secretion. RAB27B Protein, Human (HEK293) is the recombinant human-derived RAB27B protein, expressed by HEK293 , with tag free.

RAB27B 是一种小型 GTP 酶，在其活性 GTP 结合状态和非活性 GDP 结合状态之间经历动态循环，对晚期内吞途径的稳态发挥调节控制。在其活性状态下，RAB27B 与多种效应蛋白结合，有助于协调内体定位、成熟和分泌过程。值得注意的是，它通过促进 NTRK2/TRKB 与 KLC1 的结合，在促进 NTRK2/TRKB 的轴突顺行运输中发挥着至关重要的作用。此外，RAB27B 可能参与尿斑蛋白向尿路上皮顶膜的靶向，表明其参与专门的膜运输事件。

Human

HEK293

Tag Free

O00194 (T2-K215)

5874  [NCBI]

Full Length of Mature Protein

Approximately 27 kDa,based on SDS-PAGE under reducing conditions.

Greater than 85% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.