UB2E2 蛋白, Human (sf9)

The UB2E2 protein is a key ubiquitin-proteasome system participant, acting as an E2 ubiquitin-conjugating enzyme that accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to proteins. In vitro, UB2E2 exhibits multifunctionality by catalyzing polyubiquitination of “Lys-11,” “Lys-48,” and “Lys-63” linkages, suggesting its involvement in diverse cellular processes. UB2E2 Protein, Human (sf9) is the recombinant human-derived UB2E2 protein, expressed by sf9 insect cells , with tag free.

UB2E2 是泛素-蛋白酶体系统中的关键参与者，充当 E2 泛素结合酶，从 E1 复合物中接受泛素并催化其与其他蛋白质的共价附着。在体外，UB2E2 通过催化“Lys-11”、“Lys-48”和“Lys-63”连接的多泛素化展示了其多功能性，表明其参与多种细胞过程。此外，UB2E2 显示出催化甲型流感病毒 NS1 蛋白 ISGylation 的独特能力，进一步扩展其功能库并突出其在抗病毒反应中的重要性。这种多方面的活性强调了 UB2E2 在细胞调节网络内的蛋白质修饰和降解途径中的关键作用。

Human

Sf9 insect cells

Tag Free

Q96LR5 (S2-T201)

7325

Full Length of Mature Protein

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, pH 7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.