2. 重组蛋白
  3. CD Antigens
  4. Stem Cell CD Proteins Endothelial cell CD Proteins
  5. VCAM-1/CD106
  6. VCAM-1/CD106 蛋白, Human (Biotinylated, HEK293, hFc)

VCAM-1/CD106 蛋白, Human (Biotinylated, HEK293, hFc)

目录号: HY-P78948
产品使用指南

内皮细胞上表达的 VCAM-1/CD106 蛋白通过整合素相互作用严格调节白细胞粘附，在炎症过程中启动钙通道激活和 RAC1 介导的跨内皮迁移。VCAM-1/CD106 蛋白, Human (Biotinylated, HEK293, hFc) 是重组的 VCAM-1/CD106 蛋白，由 HEK293 表达，带有 C-hFc 标签。VCAM-1/CD106 蛋白, Human (Biotinylated, HEK293, hFc) 全长 673 个氨基酸，分子量约为 ~101 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

VCAM-1/CD106 proteins expressed on endothelial cells critically regulate leukocyte adhesion through integrin interactions, initiating calcium channel activation and RAC1-mediated transendothelial migration during inflammation. VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc) is the recombinant human-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc) is 673 a.a., with molecular weight of ~101 kDa.
研究背景

VCAM-1/CD106 是一种主要在内皮细胞上表达的细胞粘附糖蛋白，在免疫监视和炎症中发挥着关键作用。作为白细胞粘附到内皮的主要调节因子，它与各种整合素相互作用，影响免疫细胞的相互作用。在炎症反应期间，VCAM-1 与激活的内皮细胞上的配体结合，启动钙通道激活和 RAC1 小 GTP 酶激活，促进白细胞跨内皮迁移。此外，VCAM-1 充当进入骨髓的质量控制检查点，在主要组织相容性复合体 (MHC) I 类呈现的背景下提供“不要吃我”信号。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

P19320 (F25-E697)
基因 ID
蛋白结构
N-term
VCAM-1 (F25-E697)
Accession # P19320
hFc
C-term
同用名
Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; VCAM1; L1CAM
分子量

Approximately 101 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc)
目录号：
HY-P78948
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z