1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2 nsp14-IN-2

SARS-CoV-2 nsp14-IN-2 是一种有效的SARS-CoV-2 Nsp14 甲基转移酶 (SARS-CoV-2 Nsp14 methyltransferase) 抑制剂,IC50 值为 0.093 µM。SARS-CoV-2 nsp14-IN-2 显示出抗病毒活性 SARS-CoV-2 nsp14-IN-2 显示血浆和肝脏 S9 稳定性。SARS-CoV-2 nsp14-IN-2 具有研究 COVID-19 的潜力。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SARS-CoV-2 nsp14-IN-2 Chemical Structure

SARS-CoV-2 nsp14-IN-2 Chemical Structure

CAS No. : 2816165-16-7

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SARS-CoV-2 nsp14-IN-2 is a potent SARS-CoV-2 Nsp14 methyltransferase inhibitor with an IC50 value of 0.093 µM. SARS-CoV-2 nsp14-IN-2 shows antiviral activity. SARS-CoV-2 nsp14-IN-2 shows plasma and liver S9 stability. SARS-CoV-2 nsp14-IN-2 has the potential for the research of COVID-19[1].

IC50 & Target

IC50: 0.093 µM (SARS-CoV-2 Nsp14 methyltransferase)[1].

体外研究
(In Vitro)

SARS-CoV-2 nsp14-IN-2 (compound 10) (0-100 µM) shows antiviral activity with an EC50 value of 0.72 µM and CC50 value of >100 µM[1].
SARS-CoV-2 nsp14-IN-2 (24 h) shows plasma stability with t1/2s of >24, >24 h for human and mouse, respectively[1].
SARS-CoV-2 nsp14-IN-2 (45 min) shows liver S9 stability with t1/2 values of 842 min and >45 min in Phase I and phase II in human liver, respectively; and t1/2 values of 28.9 min and >45 min in Phase I and phase II in mouse liver, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

455.49

Formula

C21H21N5O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SARS-CoV-2 nsp14-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
SARS-CoV-2 nsp14-IN-2
目录号:
HY-150681
需求量: