1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 636 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

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  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

& Advantages

•   A unique collection of 636 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
A collection of 636 GPCR/G Protein related compounds supplied as pre-dissolved DMSO solutions or Solid
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G Protein Compound Library

Source: MedChem Express

Contents of GPCR/G Protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Fosaprepitant (dimeglumine) Pimavanserin tartrate Angiotensin II 5-valine Angiotensin II human Bradykinin Oxytocin (acetate) Octreotide (acetate) Histamine Desmopressin (Acetate) Terlipressin Empty
b Empty Gonadorelin (acetate) Leuprolide Acetate Alarelin (Acetate) Buserelin (Acetate) Goserelin (acetate) Nicotinamide N-oxide Abarelix L-Glutamine Eucalyptol Allantoin Empty
c Empty L-Glutamic acid monosodium salt trans-ACPD Theophylline Theobromine Flopropione Carbamoylcholine (chloride) L-Epinephrine DL-Epinephrine O-Phospho-L-serine Dopamine (hydrochloride) Empty
d Empty Octopamine (hydrochloride) Scopine (hydrochloride) Methacholine (chloride) Bethanechol (chloride) Tolazoline (hydrochloride) L-DOPA TCN238 Xanthotoxol (R)-(-)-Phenylephrine (hydrochloride) Synephrine (hydrochloride) Empty
e Empty SQ22536 Betahistine (dihydrochloride) (RS)-MCPG (S)-MCPG Atipamezole Methoxyphenamine (Hydrochloride) Ferulic acid (sodium) Adrenalone (hydrochloride) Detomidine (hydrochloride) E4CPG Empty
f Empty Agmatine (sulfate) RU 24969 MPEP (Hydrochloride) BRL 54443 Lorcaserin (Hydrochloride) Melatonin VU0364770 Cevimeline (hydrochloride) Arecoline (hydrobromide) Levodropropizine Empty
g Empty MTEP (hydrochloride) Dexmedetomidine (hydrochloride) Medetomidine (hydrochloride) Tetrahydrozoline (hydrochloride) Acefylline L-(-)-α-Methyldopa (hydrate) Proxyphylline CB-7921220 Moxonidine Agomelatine Empty
h Empty HOKU-81 Osthole Pilocarpine (Hydrochloride) Tasimelteon Naphazoline (hydrochloride) Isoprenaline (hydrochloride) Matrine Atipamezole (hydrochloride) Epinastine Oxidopamine (hydrobromide) Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Clorprenaline hydrochloride Cimetidine Diphylline Irsogladine Eltoprazine (hydrochloride) Xylazine (hydrochloride) Ramelteon Setiptiline VU0361737 Ethamsylate Empty
b Empty Mirtazapine Doxofylline Pemirolast (potassium) Atenolol Clonidine (hydrochloride) Sulfisoxazole VUF10460 Oncrasin-1 Piperoxan (hydrochloride) Meptazinol (hydrochloride) Empty
c Empty Terbutaline (sulfate) JNJ-7777120 DREADD agonist 21 Xylometazoline (hydrochloride) B-HT 920 Guanfacine (hydrochloride) Reparixin Dexpramipexole (dihydrochloride) Pramipexole (dihydrochloride) Tropicamide Empty
d Empty Tropisetron Alprenolol (hydrochloride) Zolmitriptan O-desmethyl Mebeverine alcohol (hydrochloride) Salbutamol (hemisulfate) Adrafinil L-Hyoscyamine Tizanidine (hydrochloride) WZ811 Guanabenz (Acetate) Empty
e Empty SKF 38393 (hydrochloride) Diphenhydramine (hydrochloride) Tripelennamine (hydrochloride) MSX-122 Dopamine serotonin antagonist-1 Amitraz PHCCC Nuciferine Pizotifen Propranolol (hydrochloride) Empty
f Empty Fenspiride (Hydrochloride) Ropinirole (hydrochloride) ST034307 AH 6809 Piribedil Vortioxetine Metoclopramide Ticlopidine (hydrochloride) Mianserin (hydrochloride) Antazoline (hydrochloride) Empty
g Empty Desipramine hydrochloride Chlorphenoxamine Lificiguat VU 0357121 GSK137647A CASIN Histamine (phosphate) 1A-116 DC260126 Alcaftadine Empty
h Empty Betaxolol NECA Sotalol (hydrochloride) BQCA ML-098 Desloratadine Lodoxamide Cyclobenzaprine (hydrochloride) Olanzapine JWH-133 Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty N-Desmethylclozapine Molindone (hydrochloride) Amezinium (methylsulfate) Clenbuterol (hydrochloride) ICI 118,551 (hydrochloride) Lu AF21934 Rotigotine AZD4635 Ramosetron (Hydrochloride) Moxisylyte (hydrochloride) Empty
b Empty Chlorprothixene (1R,2S)-VU0155041 CYM-5541 Pregnenolone JNJ-63533054 Metaraminol (tartrate) RS 127445 AVex-73 hydrochloride Diphenylpyraline (hydrochloride) SB-334867 (free base) Empty
c Empty Ro 67-7476 Imidafenacin Tropisetron (Hydrochloride) Promazine (hydrochloride) Promethazine (hydrochloride) Asenapine (hydrochloride) Piperidolate Ritodrine (hydrochloride) Cyproheptadine (hydrochloride) SCH 23390 (hydrochloride) Empty
d Empty Dolasetron JNJ16259685 UNBS5162 Clozapine Tranilast (trans-) Tranilast Azaperone Loxapine Carteolol (hydrochloride) ABT-239 Empty
e Empty Alosetron (Hydrochloride) Nizatidine Esmolol (hydrochloride) Pitolisant (hydrochloride) Palonosetron (Hydrochloride) L-Epinephrine (Bitartrate) BQU57 Proglumide YL0919 Norepinephrine (bitartrate monohydrate) Empty
f Empty ZM241385 Famotidine Isoxsuprine hydrochloride Trihexyphenidyl (hydrochloride) Topiramate Tetrahydroberberine Pumosetrag Hydrochloride Phenoxybenzamine (hydrochloride) CP-809101 (hydrochloride) Sulpiride Empty
g Empty Levosulpiride VU0152100 (R)-5-Hydroxymethyl Tolterodine Betaxolol (hydrochloride) Levobetaxolol (hydrochloride) SCH 58261 Diphenidol (hydrochloride) BD1063 (dhydrochloride) Cortodoxone GW9508 Empty
h Empty Biperiden (Hydrochloride) OC000459 Acrivastine Granisetron (Hydrochloride) N6-Cyclohexyladenosine MDA 19 Ranitidine (hydrochloride) Cyproheptadine (hydrochloride sesquihydrate) Clomipramine (hydrochloride) GR79236 Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty LY 344864 Rotigotine (Hydrochloride) rac-Rotigotine (Hydrochloride) SB225002 Prostaglandin E2 Ro 10-5824 (dihydrochloride) Dimemorfan (phosphate) SB-742457 Metoclopramide (hydrochloride hydrate) Nomifensine (maleate) Empty
b Empty Seratrodast Chlorpromazine (hydrochloride) Rotundine Homatropine (Bromide) SB-408124 Pheniramine (Maleate) Cinacalcet Oxybutynin Prednisone Salirasib Empty
c Empty Glucagon receptor antagonists-2 Glucagon receptor antagonists-3 Piperidolate (hydrochloride) BAY 41-2272 Cortisone Prednisolone Calcium-Sensing Receptor Antagonists I Dapiprazole (hydrochloride) Clemizole (hydrochloride) Hydrocortisone Empty
d Empty Solifenacin TY-52156 Labetalol (hydrochloride) Adenosine 5'-monophosphate monohydrate Sinomenine hydrochloride Ondansetron (hydrochloride dihydrate) Prucalopride Cinnarizine ADX-47273 Amisulpride Empty
e Empty Piboserod VU0357017 (hydrochloride) Homatropine (methylbromide) Rebamipide Nedocromil N6-(2-Phenylethyl)adenosine Xanomeline (oxalate) Epiberberine (chloride) Naratriptan (hydrochloride) Meprednisone Empty
f Empty Acebutolol (hydrochloride) N6-(4-Hydroxybenzyl)adenosine Prasugrel Olopatadine (hydrochloride) Methylprednisolone Haloperidol Setiptiline (maleate) Phentolamine (mesylate) Naltrexone (Hydrochloride) Ambrisentan Empty
g Empty Vortioxetine (hydrobromide) SB-222200 Talnetant Misoprostol Loratadine PD 117519 Veralipride Quetiapine Fenoterol (hydrobromide) Scopolamine (hydrobromide) Empty
h Empty Y16 Istradefylline Roxatidine (Acetate Hydrochloride) AMD-070 (hydrochloride) Azasetron (hydrochloride) Ciproxifan (maleate) MK-6892 (RS)-Butyryltimolol Atropine (sulfate monohydrate) Doxylamine (succinate) Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty AZD1981 Triflupromazine (hydrochloride) SB-269970 (hydrochloride) Alfuzosin Diphenmanil (methylsulfate) Regadenoson Flibanserin Chlorpheniramine (maleate) Dexchlorpheniramine (maleate) Rauwolscine (hydrochloride) Empty
b Empty Yohimbine (Hydrochloride) Rizatriptan (benzoate) CTEP Betamethasone Dexamethasone Naftopidil Deoxycholic acid SB-408124 (Hydrochloride) Cinacalcet (hydrochloride) Oxybutynin (chloride) Empty
c Empty Triamcinolone SB 242084 Ketanserin Mirabegron SCH 527123 TCS-OX2-29 Methscopolamine (bromide) Glycopyrrolate Solifenacin (hydrochloride) Benzetimide (hydrochloride) Empty
d Empty Asenapine (maleate) Fenoldopam (mesylate) Setipiprant Formoterol (Fumarate) Cortisone (acetate) Benztropine (mesylate) Bambuterol (hydrochloride) Perphenazine ONO-AE3-208 Ozanimod Empty
e Empty Hydrocortisone (acetate) TBPB Adoprazine GPR120-IN-1 MK-0557 Carvedilol Tozadenant CPPHA Carbinoxamine maleate salt Thioridazine (hydrochloride) Empty
f Empty ML141 Terutroban Trazodone (hydrochloride) Tamsulosin NPS-2143 PF-04418948 Org 27569 Forskolin Trimipramine (maleate) Pergolide (mesylate) Empty
g Empty SKF-82958 (hydrobromide) Ipratropium (bromide) Decloxizine (dihydrochloride) Noscapine Sumatriptan (succinate) Lasmiditan (hydrochloride) CJ-42794 Asimadoline Deoxycholic acid sodium salt Puerarin Empty
h Empty Desonide Tegaserod (maleate) RS 504393 Azelastine (hydrochloride) Palosuran TC-G-1008 MRE-269 PF-3274167 Prazosin (hydrochloride) Clopidogrel (hydrogen sulfate) Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty 4-IBP Mepenzolate (Bromide) ML314 Buspirone (hydrochloride) Methylbenactyzium Bromide Riociguat Losartan Pirenzepine (dihydrochloride) Zibotentan RBC8 Empty
b Empty Trimethobenzamide hydrochloride CID 16020046 Ketotifen (fumarate) Domperidone Fevipiprant Iloperidone Paliperidone RS102895 (hydrochloride) BML-190 Mozavaptan Empty
c Empty Pimavanserin Flavoxate (hydrochloride) Trospium (chloride) AdipoRon Irbesartan ADL-5859 ZK756326 (dihydrochloride) Reparixin (L-lysine salt) Mifepristone Budesonide Empty
d Empty EHop-016 LY310762 Lafutidine (S)-Timolol (Maleate) Latanoprost Brexpiprazole Triamcinolone (acetonide) Dexamethasone (acetate) BX471 Cevimeline (hydrochloride hemihydrate) Empty
e Empty Brompheniramine (maleate) Valsartan Laropiprant Methylnaltrexone (Bromide) BD-1047 (dihydrobromide) Dolasetron (Mesylate hydrate) Scopolamine (butylbromide) Candesartan Sertindole SA4503 (dihydrochloride) Empty
f Empty Deflazacort Vilazodone Quetiapine (fumarate) Nebivolol (hydrochloride) UK 14,304 (tartrate) NPS-2143 (hydrochloride) BPTU Loxapine (succinate) Olmesartan MK-3697 Empty
g Empty Hydroxyzine (dihydrochloride) JTC-801 Aripiprazole Propantheline (bromide) TG6-10-1 SB-674042 MBX-2982 Tolvaptan GW842166X K-Ras(G12C) inhibitor 12 Empty
h Empty Kobe0065 Naltrindole (hydrochloride) ST-836 (hydrochloride) Cabergoline Fluocinolone (Acetonide) Bay 59-3074 Cenerimod CCG-63808 CCG-1423 AMG 837 (calcium hydrate) Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Azilsartan AM095 (free acid) GSK1292263 MLE-4901 Terazosin (hydrochloride dihydrate) Clemastine (fumarate) Alvimopan (dihydrate) Ponesimod Losartan (potassium) Loxiglumide Empty
b Empty ONO-7300243 Cetirizine (dihydrochloride) Bilastine Cariprazine (hydrochloride) Cisapride Sarpogrelate (hydrochloride) Mebeverine (hydrochloride) Loteprednol Etabonate Clobetasol propionate Ziprasidone (hydrochloride monohydrate) Empty
c Empty Almotriptan (malate) Dimenhydrinate TCS 1102 Tiotropium (Bromide) MRS 2578 Alverine (citrate) Naftidrofuryl (oxalate) Lixivaptan NAN-190 (hydrobromide) Methylprednisolone succinate Empty
d Empty Ki16425 SRT3190 Dinoprost (tromethamine salt) (20S)-Protopanaxatriol Sitaxsentan (sodium) Ebrotidine APD668 Vilazodone (Hydrochloride) AM095 Taprenepag Empty
e Empty Avosentan IT1t (dihydrochloride) GSK682753A Trifluoperazine (dihydrochloride) Solifenacin (Succinate) Pranlukast PF429242 (dihydrochloride) SB-399885 hydrochloride Nicergoline Prucalopride (succinate) Empty
f Empty (±)-SLV319 SB 271046 (Hydrochloride) Pranlukast (hemihydrate) AM966 Grapiprant Vorapaxar Fluocinonide Silodosin NS-304 Rimonabant (Hydrochloride) Empty
g Empty Rolapitant Fluticasone (propionate) Fimasartan Plerixafor Trimebutine (maleate) Preladenant AM630 Betamethasone dipropionate Ivabradine (hydrochloride) Nefazodone (hydrochloride) Empty
h Empty BAN ORL 24 Darifenacin (hydrobromide) Clebopride (malate) Indacaterol (maleate) Otenabant Fluphenazine (dihydrochloride) Almorexant Loperamide (hydrochloride) Baohuoside I Telmisartan Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Taranabant Siponimod AC-55541 GW-1100 Eprosartan (mesylate) Beclometasone dipropionate Mometasone furoate Azatadine (dimaleate) Ticagrelor WIN 55,212-2 (Mesylate) Empty
b Empty TAK-875 NSC 23766 (trihydrochloride) Rupatadine (Fumarate) Aprepitant Conivaptan (hydrochloride) CGS 21680 (Hydrochloride) Fexofenadine (hydrochloride) JDTic (dihydrochloride) WAY-100635 (maleate salt) Ciclesonide Empty
c Empty 2-Cl-IB-MECA Ketanserin (tartrate) UNC0642 Anamorelin Bepotastine (Beslilate) Doxazosin (mesylate) Bosentan AM251 [Leu5]-Enkephalin Adomeglivant Empty
d Empty Dronedarone Tarafenacin (D-tartrate) Olmesartan (medoxomil) Otilonium (bromide) GRA Ex-25 Aclidinium (Bromide) lumateperone (Tosylate) MK-0974 PF-4136309 Bosentan (hydrate) Empty
e Empty [D-Ala2]leucine-enkephalin JD-5037 Tyr-Gly-Gly-Phe-Met-OH Zafirlukast Netupitant EHT 1864 Anamorelin (hydrochloride) ZCL278 Orexin 2 Receptor Agonist Macitentan Empty
f Empty 6H05 (trifluoroacetate) MK-3207 (Hydrochloride) Salmeterol (xinafoate) Montelukast (sodium) Candesartan (Cilexetil) Endomorphin 1 Mosapride (citrate) NKP608 Ibutamoren (Mesylate) Elagolix Empty
g Empty Metoprolol (Succinate) Capromorelin (Tartrate) Dihydroergotamine (mesylate) PD 123319 (ditrifluoroacetate) Batefenterol Neuromedin N TRAP-6 (±)-Bisoprolol (hemifumarate) Plerixafor (octahydrochloride) Mebhydrolin (napadisylate) Empty
h Empty Diquafosol (tetrasodium) Gallamine Triethiodide AMD 3465 (hexahydrobromide) Angiotensin (1-7) LCZ696 Carbetocin Empty Empty Empty Empty Empty
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GPCR/G Protein Compound Library

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