1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 732 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

GPCR/G Protein Compound Library
Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

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  • Description

  • Product Details

  • Composition

  • Contents

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& Advantages

•   A unique collection of 732 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
A collection of 732 GPCR/G Protein related compounds supplied as pre-dissolved DMSO solutions or Solid
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G Protein Compound Library

Source: MedChem Express

Contents of GPCR/G Protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PD 117519 NPS-2143 Taranabant 4-IBP DREADD agonist 21 Lu AF21934 (RS)-MCPG SQ22536 Ro 67-7476 (S)-MCPG Empty
b Empty JNJ16259685 PHCCC TCS-OX2-29 Plerixafor Bay 59-3074 Aprepitant Flopropione VU0364770 Ticagrelor YL0919 Empty
c Empty Piperoxan (hydrochloride) Zibotentan ONO-7300243 Norbinaltorphimine dihydrochloride ZK756326 (dihydrochloride) AR-M 1000390 (hydrochloride) Ocaperidone SB-224289 hydrochloride Naltrindole (hydrochloride) Vorapaxar Empty
d Empty GSK682753A Silodosin Agmatine (sulfate) ST034307 Phenylbiguanide Ro 10-5824 (dihydrochloride) Nicotinamide N-oxide Vanilpyruvic acid CYM-5541 VUF10460 Empty
e Empty IT1t (dihydrochloride) GPR120-IN-1 NPS-2143 (hydrochloride) Veralipride N6-(2-Phenylethyl)adenosine BQCA CB-7921220 AVex-73 hydrochloride DC260126 Prostaglandin E2 Empty
f Empty Navarixin AZD4635 (RS)-Butyryltimolol PD 123319 (ditrifluoroacetate) TC-G-1008 MK-3207 (Hydrochloride) E7046 SB-399885 hydrochloride LY334370 5'-N-Ethylcarboxamidoadenosine Empty
g Empty SB297006 WAY-100635 Maleate BETP 1A-116 MK-2894 MK-2894 (sodium salt) AH 6809 SKF-82958 (hydrobromide) Fasiglifam JDTic (dihydrochloride) Empty
h Empty Ketanserin Ketanserin (tartrate) Sarpogrelate (hydrochloride) Ponesimod Palosuran MK-6892 Pridopidine Asimadoline VU 0365114 CGP71683 hydrochloride Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Methiothepin mesylate CJ-42794 Almorexant Almorexant (hydrochloride) Teijin compound 1 (Z)-Thiothixene CCG-203971 Otenabant Istradefylline Preladenant Empty
b Empty RO1138452 SB-334867 (free base) SB-674042 TCS 1102 Tozadenant (+)-PD 128907 hydrochloride Fingolimod Asenapine (maleate) Sitaxsentan (sodium) ONC212 Empty
c Empty ALB-127158(a) LP-211 Desisobutyryl-ciclesonide 8-OH-DPAT Chlorcyclizine (hydrochloride) N-Acetylhistamine VU0467154 AZ3451 MBQ-167 Fingolimod (hydrochloride) Empty
d Empty GSK1292263 BX471 VU 0238429 JNJ-5207852 ABT-239 Pitolisant (hydrochloride) Ozanimod MK-3697 Siponimod Namodenoson Empty
e Empty BAY 41-2272 Atipamezole (hydrochloride) Atipamezole Angiotensin (1-7) 6H05 (trifluoroacetate) SKF 38393 (hydrochloride) Terlipressin Gonadorelin (acetate) Y16 Prucalopride (succinate) Empty
f Empty Bromocriptine (mesylate) Piribedil Rauwolscine (hydrochloride) Trimethobenzamide hydrochloride ML141 EHop-016 RBC8 CASIN BQU57 Dinoprost (tromethamine salt) Empty
g Empty Batefenterol Pimozide MK-0354 SRT3190 ADL-5859 ADX-47273 (R)-ADX-47273 MRS 2578 WAY-100635 (maleate salt) CGS 21680 (Hydrochloride) Empty
h Empty Biperiden (Hydrochloride) MTEP (hydrochloride) Ambrisentan AM211 BRL 54443 BAN ORL 24 PF-4136309 JTC-801 Ki16425 Org 27569 Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty WIN 55,212-2 (Mesylate) Montelukast (sodium) VU0152100 TAK-779 SB 242084 SB 242084 (hydrochloride) Xanomeline (oxalate) SR144528 PF429242 (dihydrochloride) Nedocromil Empty
b Empty CID-1067700 JNJ-7777120 SA4503 (dihydrochloride) Rupatadine (Fumarate) LY310762 Abarelix Betamethasone Betamethasone dipropionate Beclometasone dipropionate Budesonide Empty
c Empty Clobetasol propionate Deflazacort Leuprolide Acetate Goserelin (acetate) Mifepristone Mometasone furoate MSX-122 Norepinephrine (bitartrate monohydrate) Noscapine Pergolide (mesylate) Empty
d Empty LY 344864 LY 344864 racemate IPSU BPTU Angiotensin II human ICI 118,551 (hydrochloride) Telmisartan ZCL278 AMG 837 (calcium hydrate) UNC0642 Empty
e Empty CCG-1423 CP 376395 Rimonabant (Hydrochloride) Aclidinium (Bromide) Cisapride Prucalopride Tegaserod (maleate) GW842166X Macitentan Lixivaptan Empty
f Empty TGR5 Receptor Agonist Vilazodone (Hydrochloride) Vilazodone Lodoxamide Indacaterol (maleate) Salmeterol SB 271046 (Hydrochloride) SB-742457 AC-55541 Elagolix sodium Empty
g Empty (1R,2S)-VU0155041 VU0361737 TCN238 MLE-4901 Bilastine JNJ-31020028 Latrepirdine (dihydrochloride) Haloperidol Clozapine Olanzapine Empty
h Empty Sertindole Quetiapine Amisulpride Aripiprazole Talnetant Pimavanserin Pimavanserin tartrate Tandospirone TBPB L-Glutamic acid monosodium salt Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty MPEP (Hydrochloride) CPPHA Dexamethasone Dexamethasone (acetate) Anamorelin Anamorelin (hydrochloride) Rolapitant Salirasib Cariprazine (hydrochloride) Mirabegron Empty
b Empty Riociguat Adoprazine Elagolix (±)-SLV319 Tasimelteon Tarafenacin (D-tartrate) Lasmiditan (hydrochloride) NS-304 Taprenepag Azilsartan Empty
c Empty Lificiguat Volinanserin OPC-21268 PF-3274167 Sinomenine hydrochloride O-Phospho-L-serine Avosentan ST-836 (hydrochloride) Capromorelin (Tartrate) Reparixin Empty
d Empty Reparixin (L-lysine salt) AM966 Prasugrel Ciproxifan (maleate) MBX-2982 Cabergoline OC000459 SB-269970 (hydrochloride) Forskolin VU 0357121 Empty
e Empty rac-Rotigotine (Hydrochloride) MK-0557 Vortioxetine Vortioxetine (hydrobromide) RS 504393 RS 127445 BML-190 AM630 AM251 CTEP Empty
f Empty INCB 3284 MDA 19 PRX-08066 VU 0364439 WZ811 Ebrotidine CP-809101 (hydrochloride) AR 231453 APD668 Piboserod Empty
g Empty GW9508 MK-7622 Kobe0065 SB-222200 NSC 23766 (trihydrochloride) Dobutamine (hydrochloride) Brexpiprazole Eprosartan (mesylate) AdipoRon JWH-133 Empty
h Empty LY2119620 AZD1981 AMD 3465 (hexahydrobromide) AM095 AM095 (free acid) Diphenmanil (methylsulfate) Metipranolol hydrochloride Netupitant UNBS5162 Asenapine (hydrochloride) Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Setipiprant ML314 LY2828360 EHT 1864 Oncrasin-1 PSN632408 Eltoprazine (hydrochloride) RU 24969 CID 16020046 SB225002 Empty
b Empty Fevipiprant Grapiprant TG6-10-1 Terutroban BD-1047 (dihydrobromide) Tolvaptan Olmesartan Olmesartan (medoxomil) Medetomidine Dexmedetomidine (hydrochloride) Empty
c Empty Medetomidine (hydrochloride) Pirenzepine (dihydrochloride) Agomelatine Agomelatine (hydrochloride) Alcaftadine Cetirizine (dihydrochloride) Loratadine Pramipexole (dihydrochloride) Dexpramipexole (dihydrochloride) Loteprednol Etabonate Empty
d Empty Tiotropium (Bromide) Octreotide (acetate) Clozapine (N-oxide) Desmopressin (Acetate) (S)-Timolol (Maleate) Metoclopramide Metoclopramide (hydrochloride hydrate) Loxapine Loxapine (succinate) Alarelin (Acetate) Empty
e Empty Ziprasidone (hydrochloride monohydrate) Iloperidone Guanfacine (hydrochloride) Tripelennamine (hydrochloride) Salmeterol (xinafoate) Clopidogrel (hydrogen sulfate) Cortisone Cortisone (acetate) Prednisolone Glycopyrrolate Empty
f Empty Zafirlukast Carteolol (hydrochloride) Acebutolol (hydrochloride) Atenolol Bambuterol (hydrochloride) Metoprolol (Succinate) Candesartan (Cilexetil) Losartan Losartan (potassium) Oxytocin (acetate) Empty
g Empty Carbetocin Mepenzolate (Bromide) Cenerimod Nastorazepide NKP608 PRE-084 (hydrochloride) BD1063 (dhydrochloride) Valsartan LCZ696 Mozavaptan Empty
h Empty Conivaptan (hydrochloride) RS102895 (hydrochloride) Bremelanotide (Acetate) N6-[2-(4-Aminophenyl)ethyl]adenosine JD-5037 Tranilast (trans-) K-Ras(G12C) inhibitor 12 N6-(4-Hydroxybenzyl)adenosine N6-Cyclohexyladenosine LY354740 Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PF-04418948 GR79236 Orexin 2 Receptor Agonist L755507 trans-ACPD GSK2018682 ZM241385 SCH 58261 SCH 23390 (hydrochloride) JNJ-46778212 Empty
b Empty Pumosetrag Hydrochloride BIBS 39 lumateperone (Tosylate) TY-52156 VU0357017 (hydrochloride) ML-098 NAN-190 (hydrobromide) JNJ-63533054 Adomeglivant MK-571 (sodium salt) Empty
c Empty GSK137647A Xanthotoxol Clemizole (hydrochloride) Setiptiline Setiptiline (maleate) MK-0974 Dopamine serotonin antagonist-1 CCR2-RA-[R] AMD-070 hydrochloride Glucagon receptor antagonists-2 Empty
d Empty Glucagon receptor antagonists-3 Laropiprant HOKU-81 GRA Ex-25 GW-1100 Calcium-Sensing Receptor Antagonists I Ibutamoren (Mesylate) ONO-AE3-208 LY404039 Plerixafor (octahydrochloride) Empty
e Empty Cevimeline (hydrochloride) Cinacalcet Cinacalcet (hydrochloride) Alosetron (Hydrochloride) SB-408124 CCG-63808 Rotigotine Methylnaltrexone (Bromide) (R)-5-Hydroxymethyl Tolterodine SB-408124 (Hydrochloride) Empty
f Empty Alvimopan (monohydrate) Alvimopan (dihydrate) Cevimeline (hydrochloride hemihydrate) Cortodoxone MRE-269 Solifenacin (Succinate) Rotigotine (Hydrochloride) B-HT 920 Darifenacin (hydrobromide) Bosentan Empty
g Empty Bosentan (hydrate) Ramelteon Bepotastine (Beslilate) Dronedarone Paliperidone Palonosetron (Hydrochloride) Fenspiride (Hydrochloride) Solifenacin Tolazoline (hydrochloride) Doxylamine (succinate) Empty
h Empty Decloxizine (dihydrochloride) Perphenazine Mebeverine (hydrochloride) Fluphenazine (dihydrochloride) Diphenidol (hydrochloride) Methacholine (chloride) Flibanserin Alizapride hydrochloride Histamine (phosphate) Dapiprazole (hydrochloride) Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Zuclopenthixol Regadenoson Adenosine 5'-monophosphate monohydrate Amezinium (methylsulfate) Doxofylline Carvedilol Formoterol (Fumarate) Tropisetron (Hydrochloride) Quetiapine (fumarate) Azasetron (hydrochloride) Empty
b Empty Granisetron (Hydrochloride) Tropisetron Melatonin (±)-Bisoprolol (hemifumarate) Doxazosin (mesylate) Pizotifen Sumatriptan (succinate) Topiramate Diphylline Pregnenolone Empty
c Empty Ticlopidine (hydrochloride) Fluticasone (propionate) Ketotifen (fumarate) Lafutidine Ivabradine (hydrochloride) Detomidine (hydrochloride) Azatadine (dimaleate) Mianserin (hydrochloride) Mosapride (citrate) Alfuzosin Empty
d Empty Prazosin (hydrochloride) Tizanidine (hydrochloride) Tranilast Naratriptan (hydrochloride) Irbesartan Nebivolol (hydrochloride) Candesartan Rizatriptan (benzoate) Prednisone L-(-)-α-Methyldopa (hydrate) Empty
e Empty Zolmitriptan Ipratropium (bromide) Desonide Methylprednisolone Oxybutynin Oxybutynin (chloride) Chlorprothixene Ranitidine (hydrochloride) Chlorpheniramine (maleate) Pranlukast Empty
f Empty Pranlukast (hemihydrate) Clemastine (fumarate) Diphenhydramine (hydrochloride) Roxatidine (Acetate Hydrochloride) Nizatidine Tropicamide Sulfisoxazole Irsogladine Triamcinolone Methscopolamine (bromide) Empty
g Empty Meclizine (dihydrochloride) Mirtazapine Rebamipide Phentolamine (mesylate) Cyproheptadine (hydrochloride) Terazosin (hydrochloride dihydrate) Moxonidine Famotidine Trimebutine (maleate) Betaxolol Empty
h Empty Betaxolol (hydrochloride) Levobetaxolol (hydrochloride) Almotriptan (malate) Naftopidil Atropine (sulfate monohydrate) Bethanechol (chloride) Clonidine (hydrochloride) Domperidone Fluocinolone (Acetonide) Gallamine Triethiodide Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Loperamide (hydrochloride) Olopatadine (hydrochloride) Phenoxybenzamine (hydrochloride) Salbutamol (hemisulfate) Sotalol (hydrochloride) Xylazine (hydrochloride) Naphazoline (hydrochloride) L-Epinephrine (Bitartrate) Dopamine (hydrochloride) Ritodrine (hydrochloride) Empty
b Empty Clomipramine (hydrochloride) Scopine (hydrochloride) Trospium (chloride) Azelastine (hydrochloride) (R)-(-)-Phenylephrine (hydrochloride) Xylometazoline (hydrochloride) Trazodone (hydrochloride) Brompheniramine (maleate) Fluocinonide Arecoline (hydrobromide) Empty
c Empty Carbazochrome (sodium sulfonate) Otilonium (bromide) Alverine (citrate) Benztropine (mesylate) Betahistine (dihydrochloride) Octopamine (hydrochloride) Trifluoperazine (dihydrochloride) Pemirolast (potassium) Desloratadine Homatropine (Bromide) Empty
d Empty Hydroxyzine (dihydrochloride) Flavoxate (hydrochloride) Tetrahydrozoline (hydrochloride) Guanabenz (Acetate) Propranolol (hydrochloride) Latanoprost Ramosetron (Hydrochloride) Diquafosol (tetrasodium) Misoprostol Ropinirole (hydrochloride) Empty
e Empty Ciclesonide Triamcinolone (acetonide) Epinastine Prednisolone (disodium phosphate) UK 14,304 UK 14,304 (tartrate) Tamsulosin Imidafenacin Dihydroergotamine (mesylate) Ebastine Empty
f Empty Nicergoline Urapidil Fenoldopam (mesylate) Cyclobenzaprine (hydrochloride) Ramatroban Dolasetron Dolasetron (Mesylate hydrate) Seratrodast Fimasartan Fexofenadine (hydrochloride) Empty
g Empty Terbutaline (sulfate) Theophylline Triflupromazine (hydrochloride) Piperidolate (hydrochloride) Piperidolate Thioridazine (hydrochloride) Diphenylpyraline (hydrochloride) Pheniramine (Maleate) Fenoterol (hydrobromide) Pindolol Empty
h Empty Molindone (hydrochloride) Sulpiride Metergoline Levosulpiride Dexchlorpheniramine (maleate) Antazoline (hydrochloride) Ethamsylate Oxidopamine (hydrobromide) Cinnarizine Naftidrofuryl (oxalate) Empty

Plate layout: HY-L006-9

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Labetalol (hydrochloride) Nomifensine Nomifensine (maleate) Amitraz Buspirone (hydrochloride) Metaraminol (tartrate) Flunisolide Cyproheptadine (hydrochloride sesquihydrate) Hydrocortisone (acetate) Propantheline (bromide) Empty
b Empty Histamine Atropine Carbamoylcholine (chloride) Trimipramine (maleate) Dimenhydrinate Promazine (hydrochloride) Droperidol Isoxsuprine hydrochloride Trihexyphenidyl (hydrochloride) Mepyramine maleate Empty
c Empty Mebhydrolin (napadisylate) Mebhydrolin Chloropyramine hydrochloride Proglumide Clorprenaline hydrochloride Homatropine (methylbromide) Esmolol (hydrochloride) Nefazodone (hydrochloride) Moxisylyte (hydrochloride) Azaperone Empty
d Empty Serotonin hydrochloride Acefylline Acrivastine Alprenolol Alprenolol (hydrochloride) Benzetimide (hydrochloride) Carbinoxamine maleate salt Chlorphenoxamine Clebopride (malate) Clenbuterol (hydrochloride) Empty
e Empty Corticosterone Proxyphylline Dexamethasone phosphate disodium Levodropropizine Methylprednisolone succinate Methylbenactyzium Bromide Scopolamine N-oxide hydrobromide Loxiglumide Mequitazine Dimemorfan (phosphate) Empty
f Empty O-desmethyl Mebeverine alcohol (hydrochloride) N-Desmethylclozapine Solifenacin (hydrochloride) Baohuoside I Ginsenoside Rb2 Nuciferine Osthole Ferulic acid (sodium) Eucalyptol Rotundine Empty
g Empty Yohimbine (Hydrochloride) Synephrine (hydrochloride) Theobromine Puerarin Matrine Epiberberine (chloride) Scopolamine (hydrobromide) Tetrahydropalmatine Scopolamine (butylbromide) L-Glutamine Empty
h Empty L-Hyoscyamine Allantoin Hydrocortisone Anisodamine Deoxycholic acid Deoxycholic acid sodium salt Ginsenoside Ro Harmine Isocorynoxeine (20S)-Protopanaxatriol Empty

Plate layout: HY-L006-10

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Tetrahydroberberine β-Caryophyllene p-Hydroxycinnamic acid Tyr-Gly-Gly-Phe-Met-OH TRAP-6 Neuromedin N Angiotensin II 5-valine Endomorphin 1 [Leu5]-Enkephalin [Des-Arg9]-Bradykinin (acetate) Empty
b Empty JMV 2959 hydrochloride Tulobuterol hydrochloride Empty Empty Empty Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty


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GPCR/G Protein Compound Library

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