2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 代谢化合物库系列
  6. 质谱人代谢物化合物库
质谱人代谢物化合物库 - Mass Spectrometry Human Metabolite Library

Cat. No.: HY-L215

代谢组学是对生物系统中的小分子代谢物进行系统表征的学科，已成为植物科学、微生物生物技术和生物医学研究领域基础研究和转化应用中不可或缺的分析平台。作为多组学整合的重要组成部分，该学科可解读在基因组、转录组和蛋白质组调控下游运行的错综复杂的分子网络，从而捕捉最接近生物体功能的动态生化表型。代谢组由分子量通常低于 1500 Da 的内源化合物组成，是细胞过程和环境相互作用的功能读数，代谢网络的扰动往往与疾病的发病机制有关。这些独特的属性促使代谢组学在药理学研究中发挥着举足轻重的作用，尤其是在靶点解构、药效学评估和病理过程的机理阐明方面。

MCE 可提供5,229质谱人体代谢物，可用于代谢物鉴定和定量、功能细胞检测和表型筛选的质谱分析。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 质谱人代谢物化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，5,126 个产品以 10 mM 浓度提供，96 个产品以 2 mM 浓度提供，7 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 5,229 mass spectrometry human metabolites for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for metabolomics analysis.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 5,229 mass spectrometry human metabolites supplied as pre-dissolved Solutions or Solid
Solution: 5,126 compounds supplied in 10 mM solution, 96 compounds supplied in 2 mM solution, 7 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

NF-κB (193)

COX (181)

Fungal (158)

HIV (107)

Akt (87)

PI3K (74)

ERK (70)

PPAR (66)

iGluR (58)

mAChR (54)

VEGFR (51)

STAT (47)

MMP (46)

JNK (44)

EGFR (43)

PDGFR (36)

mTOR (35)

HSV (33)

PKC (33)

AMPK (31)

CDK (31)

nAChR (30)

HCV (29)

c-Kit (26)

JAK (26)

Src (25)

FGFR (23)

HDAC (23)

PARP (23)

Wnt (23)

HBV (21)

mGluR (21)

FLT3 (20)

GSK-3 (20)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Mass Spectrometry Human Metabolite Library
    目录号：
    HY-L215
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