1. Metabolic Enzyme/Protease Anti-infection Apoptosis
  2. Succinate Dehydrogenase Fungal Apoptosis
  3. SDH-IN-26

SDH-IN-26 (Compound C3) 是琥珀酸脱氢酶 (SDH) 抑制剂。SDH-IN-26 对 solanrhizoctonia Botrytis cinerea 等多种植物致病真菌具有显著的抑制活性,对 solanrhizoctonia 抑制的 EC50 值为 0.270 μg/mL。SDH-IN-26 破坏真菌细胞膜的完整性,增加细胞膜通透性,破坏细胞结构,减少线粒体数量,从而影响菌丝的正常生长。SDH-IN-26 导致线粒体膜电位降低,诱导细胞凋亡 (apoptosis)。SDH-IN-26 有望用于真菌引起的植物病害的研究。

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SDH-IN-26 Chemical Structure

SDH-IN-26 Chemical Structure

1.  客户无需承担相应的运输费用。

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SDH-IN-26 (Compound C3) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-26 exhibits significant inhibitory activity against multiple phytopathogenic fungi, such as Rhizoctonia solani and Botrytis cinerea, with an EC50 value of 0.270 μg/mL against Rhizoctonia solani. SDH-IN-26 damages the integrity of the fungal cell membrane, increases membrane permeability, disrupts cell structure, and reduces the number of mitochondria, thus affecting the normal growth of mycelia. SDH-IN-26 leads to a decrease in mitochondrial membrane potential, and induces cell apoptosis. SDH-IN-26 is promising for research of plant diseases caused by fungi[1].

分子量

399.48

Formula

C20H22FN5OS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SDH-IN-26
目录号:
HY-172804
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