1. Immunology/Inflammation Metabolic Enzyme/Protease Apoptosis
  2. VAP-1 Glutathione Peroxidase
  3. SNT-8370

SNT-8370 是一种口服活性的 VAP-1 (IC50: 10 nM) 和髓过氧化物酶 (MPO) (IC50: 17 nM) 抑制剂,其对 VAP-1 和 MPO 的抑制效力比其他哺乳动物过氧化物酶高 100-1000 倍。SNT-8370 可抑制 MPO 介导的 LDL 脂质过氧化。SNT-8370 可抑制急性炎症肺损伤模型中的白细胞浸润。SNT-8370 是一种抗炎化合物,可用于炎症性疾病的研究。

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SNT-8370 Chemical Structure

SNT-8370 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SNT-8370 is an orally active inhibitor of VAP-1 (IC50: 10 nM) and myeloperoxidase (MPO) (IC50: 17 nM), with >100-1000 fold more potency for VAP-1 and MPO versus other mammalian (per)oxidases. SNT-8370 inhibits MPO-mediated LDL lipid peroxidation. SNT-8370 inhibits leukocyte infiltration in lung injury models of acute inflammation. SNT-8370 is an anti-inflammatory agent, and can be used for research of inflammatory disorders[1].

分子量

361.39

Formula

C16H16FN5O2S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SNT-8370
目录号:
HY-173596
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