2. Others Immunology/Inflammation Metabolic Enzyme/Protease
  3. Biochemical Assay Reagents Aryl Hydrocarbon Receptor Cytochrome P450
  4. Sudan IV (Standard)

Sudan IV (Standard)  (Synonyms: 苏丹IV (Standard); Solvent Red 24 (Standard); C.I. 26105 (Standard))

目录号: HY-D0932R 纯度: ≥98%
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Sudan IV (Standard) (Solvent Red 24 (Standard)) 是 Sudan IV (HY-D0932) 的分析标准品。本产品用于研究及分析应用。Sudan IV 是一种芳香烃受体 (AhR) 的激动剂，可激活下游信号通路，诱导 CYP1A1 表达。Sudan IV 通过激活 AhR-ARNT 异二聚体，结合 DNA 上的外源性反应元件 (XRE)，促进 CYP1A1 基因转录，从而增强药物代谢酶活性。Sudan IV 可用于研究工业染料的毒性机制、与血清蛋白 (如牛血清白蛋白 BSA) 的相互作用对体内分布的影响。Sudan IV 是一种脂溶性重氮染料、可用于冰冻切片上对脂类、甘油三酯和脂蛋白进行染色。

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Sudan IV (Standard) Chemical Structure

Sudan IV (Standard) Chemical Structure

CAS No. : 85-83-6

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生物活性

Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.

分子量

380.44

同用名

苏丹IV (Standard); Solvent Red 24 (Standard); C.I. 26105 (Standard)

Formula

C24H20N4O
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Sudan IV (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sudan IV (Standard)85-83-6Solvent Red 24 (Standard)C.I. 26105 (Standard)Biochemical Assay ReagentsAryl Hydrocarbon ReceptorCytochrome P450AhRCYPsInhibitorinhibitorinhibit

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