2. PI3K/Akt/mTOR Stem Cell/Wnt Cell Cycle/DNA Damage
  3. PI3K Casein Kinase
  4. Umbralisib hydrochloride (Standard)

Umbralisib hydrochloride (Standard) 

目录号: HY-12279CR 纯度: ≥98%
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Umbralisib (hydrochloride) (Standard） 是 Umbralisib (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Umbralisib (TGR-1202) hydrochloride 是一种口服有效、选择性的 PI3Kδ 和 酪蛋白激酶-1-ε (CK1ε) 双抑制剂，其 EC50 分别为 22.2 nM 和 6.0 μM。 Umbralisib hydrochloride 显示出对慢性淋巴细胞白血病 (CLL) T 细胞独特的免疫调节作用。Umbralisib hydrochloride 可用于血液系统恶性肿瘤的研究。

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Umbralisib hydrochloride (Standard) Chemical Structure

Umbralisib hydrochloride (Standard) Chemical Structure

CAS No. : 1532533-78-0

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生物活性

Umbralisib (hydrochloride) (Standard) is the analytical standard of Umbralisib (hydrochloride). This product is intended for research and analytical applications. Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.

分子量

608.01

Formula

C31H25ClF3N5O3
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Umbralisib hydrochloride (Standard) 相关分类

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Keywords:

Umbralisib hydrochloride (Standard)1532533-78-0PI3KCasein KinasePhosphoinositide 3-kinaseCLL T cellshaematological malignanciescancerlymphocytic leukemialymphomaorally activeMOLT-4 cellCD19 cellInhibitorinhibitorinhibit

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