1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Val-Cit-PAB-MMAE

Val-Cit-PAB-MMAE GMP 是 GMP 级别的 Val-Cit-PAB-MMAE (HY-100374)。Val-Cit-PAB-MMAE 是抗体偶联活性分子 ADC 的一部分,由 ADC linker (peptide Val-Cit-PAB) 和强效微管蛋白抑制剂 MMAE (HY-15162) 偶联而成。

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Val-Cit-PAB-MMAE Chemical Structure

Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 644981-35-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

体外研究
(In Vitro)

ADC 由一种抗体组成,ADC 细胞毒素通过 ADC 接头连接到该抗体上。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1123.43

Formula

C58H94N10O12

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Val-Cit-PAB-MMAE
目录号:
HY-100374G
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