2. Apoptosis
  3. Ferroptosis
  4. VEGFR-2-IN-68

VEGFR-2-IN-68 (13b) 是 VEGFR-2 的抑制剂，其 IC50 值为 41.51 nM。VEGFR-2-IN-68 (13b) 可诱导凋亡和G2/M 细胞周期阻滞。VEGFR-2-IN-68 (13b) 具有抗癌细胞转移作用。

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VEGFR-2-IN-68 Chemical Structure

VEGFR-2-IN-68 Chemical Structure

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VEGFR-2-IN-68 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VEGFR-2-IN-68 (13b) is a VEGFR-2 inhibitor, with an IC50 of 41.51 nM. VEGFR-2-IN-68 (13b) induces apoptosis and G2/M phase arrest. VEGFR-2-IN-68 (13b) exhibits anti-metastatic properties in cancer cells[1].

体外研究
(In Vitro)

VEGFR-2-IN-68 (13b) 对多种癌细胞系表现出强烈的抗增殖作用 (在 MCF-7、HCT-116 和 HepG2 细胞中的 IC50 值分别为 3.98 μM、7.66 μM 和 11.81 μM)，同时对正常细胞 (WI-38) 无显著毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

VEGFR-2-IN-68 相关抗体:
分子量

483.58

Formula

C27H25N5O2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VEGFR-2-IN-68 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEGFR-2-IN-68FerroptosisMCF-7HCT-116HepG2Inhibitorinhibitorinhibit

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