产品详情

Biological activity

•   A unique library of 1,003 diverse compounds targeting IDO.

•   Indoleamine 2,3-dioxygenase (IDO) is a heme-containing protein that catalyzes the oxidative cleavage of the C2−C3 double bond of the indole in tryptophan to provide N-formylkynurenine.

•   IDO focused library designed by a combination of structure- and ligand-based methods.

•   No PAINS (Pan Assay Interference Compounds), only medchem friendly compounds.

•   Structurally diverse.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Enamine.