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  4. (Z)-α-Cyanostilbene

(Z)-α-Cyanostilbene (化合物 8)，一种双氰基取代的丙烯腈，对 HeLa 和 HepG2 细胞具有选择性的抗增殖活性，IC50 值分别为 0.33 和 0.52 μM。

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(Z)-α-Cyanostilbene Chemical Structure

(Z)-α-Cyanostilbene Chemical Structure

CAS No. : 6114-57-4

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(Z)-α-Cyanostilbene 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Z)-α-Cyanostilbene (compound 8), a dicyano substituted acrylonitrile, shows selective antiproliferative activity against HeLa and HepG2 cells, with IC50s of 0.33 and 0.52 μM, respectively[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
64.6 μM
Compound: 7
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
[PMID: 31734024]
CFPAC-1 IC50
88.19 μM
Compound: 7
Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay
[PMID: 31734024]
HeLa IC50
48.88 μM
Compound: 7
Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
[PMID: 31734024]
HepG2 IC50
81.51 μM
Compound: 7
Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
[PMID: 31734024]
HFF IC50
93.73 μM
Compound: 7
Cytotoxicity against HFF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against HFF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 31734024]
SW-620 IC50
> 100 μM
Compound: 7
Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
[PMID: 31734024]
分子量

205.25

Formula

C15H11N
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(Z)-α-Cyanostilbene 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-α-Cyanostilbene6114-57-4Biochemical Assay ReagentsantiproliferativeHeLaHepG2Inhibitorinhibitorinhibit

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