2. 天然产物
  3. 植物 醌类
  4. 茜草科 蒽醌类
  5. 海滨木巴戟
  6. 1,5,15-Trimethylmorindol

1,5,15-Trimethylmorindol 是一种蒽醌，可从 Morinda citrifolia 叶子中分离得到。1,5,15-trimethylmorindol (25 μg/mL) 单独使用对人 T 细胞白血病细胞系 Jurkat 没有显着的细胞毒活性，但 1,5,15-Trimethylmorindol 与肿瘤坏死因子相关凋亡诱导配体 (TRAIL, 0.5-1.5 μg/mL) 联用时，显示出细胞毒性 (IC50 为 14.5-15.0 μg/mL)。

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1,5,15-Trimethylmorindol Chemical Structure

1,5,15-Trimethylmorindol Chemical Structure

CAS No. : 942609-65-6

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1,5,15-Trimethylmorindol 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC50 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay[1].

分子量

328.32

Formula

C18H16O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,5,15-Trimethylmorindol942609-65-6OthersanthraquinoneMorinda citrifoliacytotoxic activityT-cell leukemiaTRAILtumor necrosis factor-related apoptosis-inducing ligandInhibitorinhibitorinhibit

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