1. Membrane Transporter/Ion Channel
  2. Na+/Ca2+ Exchanger
  3. 12-O-Deacetyl-phomoxanthone A

12-O-Deacetyl-phomoxanthone A 是一种 钠/钙交换体1 (NCX1) 激活剂,可通过增强细胞钙信号传导,进而抑制下游 PI3K/AKT/β-catenin 通路。12-O-Deacetyl-phomoxanthone A 能诱导细胞凋亡并引发 G1 期阻滞,可用于黑色素瘤的相关研究。

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12-O-Deacetyl-phomoxanthone A Chemical Structure

12-O-Deacetyl-phomoxanthone A Chemical Structure

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Other Forms of 12-O-Deacetyl-phomoxanthone A:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

12-O-Deacetyl-phomoxanthone A, a Na+/Ca2+ exchanger 1 (NCX1) activator, causes an increase in cellular Ca2+ signaling and subsequent inhibition of the downstream PI3K/AKT/β-catenin pathway. 12-O-Deacetyl-phomoxanthone A induces apoptosis and induces G1 phase arrest. 12-O-Deacetyl-phomoxanthone A can be used in the research for melanoma[1].

分子量

708.66

Formula

C36H36O15

结构分类
初始来源

Diaporthe goulteri L17; Alternaria sp. X112

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
12-O-Deacetyl-phomoxanthone A
目录号:
HY-N15474
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