2. Membrane Transporter/Ion Channel
  3. Na+/Ca2+ Exchanger
  4. 12-O-Deacetyl-phomoxanthone A

12-O-Deacetyl-phomoxanthone A 是一种 钠/钙交换体1 (NCX1) 激活剂，可通过增强细胞钙信号传导，进而抑制下游 PI3K/AKT/β-catenin 通路。12-O-Deacetyl-phomoxanthone A 能诱导细胞凋亡并引发 G1 期阻滞，可用于黑色素瘤的相关研究。

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12-O-Deacetyl-phomoxanthone A Chemical Structure

12-O-Deacetyl-phomoxanthone A Chemical Structure

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12-O-Deacetyl-phomoxanthone A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

12-O-Deacetyl-phomoxanthone A, a Na+/Ca2+ exchanger 1 (NCX1) activator, causes an increase in cellular Ca2+ signaling and subsequent inhibition of the downstream PI3K/AKT/β-catenin pathway. 12-O-Deacetyl-phomoxanthone A induces apoptosis and induces G1 phase arrest. 12-O-Deacetyl-phomoxanthone A can be used in the research for melanoma[1].

分子量

708.66

Formula

C36H36O15
结构分类
初始来源

Diaporthe goulteri L17; Alternaria sp. X112
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

12-O-Deacetyl-phomoxanthone A 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12-O-Deacetyl-phomoxanthone ANa+/Ca2+ ExchangerInhibitorinhibitorinhibit

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