2. Immunology/Inflammation
  3. COX
  4. 4-Desmethyl-2-methyl celecoxib

4-Desmethyl-2-methyl celecoxib  (Synonyms: 4-去甲基-2-甲基塞来昔布)

目录号: HY-Z7640
产品使用指南 技术支持

4-Desmethyl-2-methyl celecoxib (Compound 1g) 是一种具有口服活性和选择性的环氧化酶-2 (COX-2) 抑制剂，IC50 值为 0.069 μM。4-Desmethyl-2-methyl celecoxib 具有抗炎、镇痛和解热活性。4-Desmethyl-2-methyl celecoxib 可以减少前列腺素的合成。4-Desmethyl-2-methyl celecoxib 有望用于炎性疾病和疼痛相关疾病的研究，如类风湿关节炎和骨关节炎。

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4-Desmethyl-2-methyl celecoxib Chemical Structure

4-Desmethyl-2-methyl celecoxib Chemical Structure

CAS No. : 170569-99-0

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规格 价格 是否有货 数量
25 mg ￥800
In-stock
50 mg ￥1264
In-stock
100 mg ￥2008
In-stock
250 mg ￥4016
询价
500 mg   询价  
1 g   询价  

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4-Desmethyl-2-methyl celecoxib 相关抗体

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COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Desmethyl-2-methyl celecoxib (Compound 1g) is an orally active and selective Cyclooxygenase-2 (COX-2) inhibitor with an IC50 value of 0.069 μM. 4-Desmethyl-2-methyl celecoxib shows anti-inflammatory, analgesic, and antipyretic activities. 4-Desmethyl-2-methyl celecoxib can reduces the synthesis of prostaglandins. 4-Desmethyl-2-methyl celecoxib is promising for research of inflammatory diseases and pain-related diseases, such as rheumatoid arthritis and osteoarthritis[1].

IC50 & Target

COX-2

0.069 μM (IC50)

分子量

381.37

Formula

C17H14F3N3O2S
CAS 号
中文名称

4-去甲基-2-甲基塞来昔布
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Desmethyl-2-methyl celecoxib 相关分类

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Keywords:

4-Desmethyl-2-methyl celecoxib170569-99-04-去甲基-2-甲基塞来昔布COXCyclooxygenaseorally activeCOX-2anti-inflammatoryanalgesicand antipyretic activitiesinflammatory diseases and pain-related diseasesInhibitorinhibitorinhibit

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