1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 6-Methyluridine

6-Methyluridine 是一种尿嘧啶核苷类似物。尿苷具有潜在的抗癫痫作用,其类似物可用于研究抗惊厥和抗焦虑活性,以及开发新型降压剂。

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6-Methyluridine Chemical Structure

6-Methyluridine Chemical Structure

CAS No. : 16710-13-7

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1 mg ¥540
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5 mg ¥1035
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10 mg ¥1710
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25 mg ¥3420
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50 mg ¥5490
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
COLO 205 IC50
> 50 μM
Compound: 18
Antitumor activity against human COLO205 cells after 3 days by WST1 assay
Antitumor activity against human COLO205 cells after 3 days by WST1 assay
[PMID: 19260677]
MCF7 IC50
> 50 μM
Compound: 18
Antitumor activity against human MCF7 cells after 3 days by WST1 assay
Antitumor activity against human MCF7 cells after 3 days by WST1 assay
[PMID: 19260677]
MDA-MB-468 IC50
> 50 μM
Compound: 18
Antitumor activity against human MDA468 cells after 3 days by WST1 assay
Antitumor activity against human MDA468 cells after 3 days by WST1 assay
[PMID: 19260677]
OCI-AML2 IC50
> 50 μM
Compound: 18
Antitumor activity against human OCI-AML2 cells after 3 days by WST1 assay
Antitumor activity against human OCI-AML2 cells after 3 days by WST1 assay
[PMID: 19260677]
OCI-Ly7 IC50
> 50 μM
Compound: 18
Antitumor activity against human OCI-LY7 cells after 3 days by WST1 assay
Antitumor activity against human OCI-LY7 cells after 3 days by WST1 assay
[PMID: 19260677]
OVCAR-4 IC50
> 50 μM
Compound: 18
Antitumor activity against human OVCAR4 cells after 3 days by WST1 assay
Antitumor activity against human OVCAR4 cells after 3 days by WST1 assay
[PMID: 19260677]
分子量

258.23

Formula

C10H14N2O6

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 50 mg/mL (193.63 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.8725 mL 19.3626 mL 38.7252 mL
5 mM 0.7745 mL 3.8725 mL 7.7450 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8725 mL 19.3626 mL 38.7252 mL 96.8129 mL
5 mM 0.7745 mL 3.8725 mL 7.7450 mL 19.3626 mL
10 mM 0.3873 mL 1.9363 mL 3.8725 mL 9.6813 mL
15 mM 0.2582 mL 1.2908 mL 2.5817 mL 6.4542 mL
20 mM 0.1936 mL 0.9681 mL 1.9363 mL 4.8406 mL
25 mM 0.1549 mL 0.7745 mL 1.5490 mL 3.8725 mL
30 mM 0.1291 mL 0.6454 mL 1.2908 mL 3.2271 mL
40 mM 0.0968 mL 0.4841 mL 0.9681 mL 2.4203 mL
50 mM 0.0775 mL 0.3873 mL 0.7745 mL 1.9363 mL
60 mM 0.0645 mL 0.3227 mL 0.6454 mL 1.6135 mL
80 mM 0.0484 mL 0.2420 mL 0.4841 mL 1.2102 mL
100 mM 0.0387 mL 0.1936 mL 0.3873 mL 0.9681 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
6-Methyluridine
目录号:
HY-152732
需求量: