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Apoptosis Inducer

Apoptosis inducer is a class of compounds that induce apoptosis, the exact mechanism is unknown or involved a series of pathways.

Apoptosis inducer (32)
产品名称 目录号 简述
(-)-Epigallocatechin Gallate HY-13653

(-)-Epigallocatechin Gallate(EGCG)是多酚类黄酮抗氧化剂,能抑制端粒酶和DNA甲基转移酶,还能阻断EGF和HER-2的受体活性。

(20S)-Protopanaxadiol HY-N0797

(20S)-Protopanaxadiol (20-Epiprotopanaxadiol)是protopanaxadiol型人参皂苷的糖苷配基代谢衍生物,为凋亡诱导剂。

(E)-[6]-Dehydroparadol HY-77293

(E)-[6]-Dehydroparadol, extracted from patent US 9272994, compound M15, shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively.

Adarotene HY-14808

Adarotene (ST1926)是细胞凋亡诱导剂,能促使DNA损伤的产生,对多种人肿瘤细胞有抗增殖活性。

Apoptosis Activator 2 HY-18633

Apoptosis Activator 2是细胞凋亡有效激活剂,能促进procaspase-9的加工并活化caspase-3。

Baohuoside I HY-N0011

Baohuoside I (Icariside-II)是朝鲜淫羊藿提取物,被证明是CXCR4表达调节剂以及癌细胞凋亡诱导剂。

Betulin HY-N0083

Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with IC50 value of 14.5 μM in K562 cell line.

Betulinic acid HY-10529

Betulinic acid能诱导肿瘤细胞凋亡,还可抑制HIV-1,EC50为1.4 _mu_ M。

Cholesterol myristate HY-N2338

Cholesterol myristate is a natural steroid present in traditional Chinese medicine.

Chondroitin sulfate HY-B2162

Chondroitin sulfate, one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis.

Cisplatin HY-17394

Cisplatin (顺铂; CDDP) 是铂复合物,能与DNA耦合干扰DNA合成。

Costunolide HY-N0036

Costunolide有抗炎和抗氧化活性,能介导凋亡。

Desacetylcinobufotalin HY-N0882

去乙酰华蟾毒它灵(Desacetylcinobufotalin)是凋亡诱导剂,天然化合物。

Ecteinascidin 770 HY-101191

Ecteinascidin 770 (ET-770) is a 1,2,3,4-tetrahydroisoquinoline alkaloid with potent anti-cancer activities; inhibits U373MG cells with an IC50 of 4.83 nM.

Elesclomol HY-12040

Elesclomol (STA-4783)是新型氧化应激诱导剂,能促肿瘤细胞凋亡。

Epibrassinolide HY-N0848

Epibrassinolide (EBR; B1105; 24-Epibrassinolide)是油菜素内酯中的一种生物活性物,能在不影响正常细胞生长的情况下,诱导多种肿瘤细胞凋亡。

Episilvestrol HY-15359

Episilvestrol是Silvestrol的衍生物,能在不激活caspase-3或-7的情况下,诱导LNCaP细胞凋亡。同时是 5'myc-UTR-LUC 抑制剂,IC50为0.8 nM。

Ginsenoside Rg6 HY-N0907

人参皂苷Rg6(Ginsenoside Rg6)是凋亡诱导剂,天然化合物。

Glycochenodeoxycholic acid HY-N2334

Glycochenodeoxycholic acid is a bile salt formed in the liver from chenodeoxycholate and glycine; used to induce hepatocyte apoptosis in research.

Honokiol HY-N0003

Honokiol(NSC-293100)由中草药厚朴中提取,有抗癌活性。

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