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DNA/RNA Synthesis

DNA/RNA Synthesis (29)
产品名称 目录号 简述
Acelarin HY-100885

Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine.

alpha-Amanitin HY-19610

alpha-Amanitin is a potent inhibitor of DNA-dependent RNA polymerase II.

Beaucage reagent HY-100951

Beaucage reagent is found to be potent in causing DNA cleavage.

Bleomycin sulfate HY-17565

Bleomycin (Blenoxane)是糖肽类抗生素,有抗癌活性,能诱导DNA链断裂。

BMH-21 HY-12484

BMH-21是一新型DNA嵌入剂(DNA intercalator),能结合rDNA并抑制RNA polymerase I的转录,不使组蛋白H2AX磷酸化。

BRD7116 HY-18714

BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity.

Capecitabine HY-B0016

Capecitabine (卡培他滨) 是口服的抗代谢类抗癌化合物。

Chebulinic acid HY-N2033

Chebulinic acid is a potent natural inhibitor of M.

COH29 HY-19931

COH29 is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity with IC50 value of 8 μM in KB cell.

CX-5461 HY-13323

CX-5461是rRNA合成抑制剂,选择性抑制Pol I驱动的rRNA转录,IC50为142nM,对Pol II无效。

Cycloheximide HY-12320

Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, with IC50 of 532.5 nM.

Deoxycytidine triphosphate HY-101400

Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis.

Gemcitabine HY-17026

Gemcitabine (吉西他滨; LY-188011; NSC 613327) 是DNA合成抑制剂,对PANC1,MIAPaCa2,BxPC3和Capan2细胞的IC50分别为50 nM,40 nM,18 nM和12 nM。

Gemcitabine Hydrochloride HY-B0003

Gemcitabine Hydrochloride (盐酸吉西他滨; LY 188011) 是DNA合成抑制剂,在PANC1,MIAPaCa2,BxPC3和Capan2细胞中IC50分别为50 nM,40 nM,18 nM和12 nM。

Guanine HY-Y1055

Guanine is one of the fundamental components of nucleic acids (DNARNA).

Hydroxyurea HY-B0313

Hydroxyurea (羟基脲) 具有抗肿瘤活性,能通过抑制核苷二磷酸还原酶来阻断DNA合成。

L189 HY-15588

L189 is a novel human DNA ligase inhibitor, inhibits hLigI/III/IV with IC50 of 5/9/5 μM.

L67 HY-15586

L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.

LMI070 HY-19620

LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

N2-Methylguanine HY-101412

N2-Methylguanine is a modified nucleoside.

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