1. Metabolic Enzyme/Protease
  2. Drug Metabolite

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Drug Metabolite 相关产品 (6):

Cat. No. Product Name Effect Purity
  • HY-17366
    Clozapine N-oxide 99.63%
    Clozapine N-oxide (CNO) 是抗精神病药物氯氮平的主要代谢产物。 Clozapine N-oxide是 DREADD 系统的激动剂。
  • HY-13318
    Oseltamivir acid 98.60%
    Oseltamivir acid,是GS 4071的乙酯前药,是流感病毒神经氨酸酶的抑制剂,IC50 约为100 nM。
  • HY-101406
    Thyroxine sulfate >98.0%
    Thyroxine sulfate是甲状腺激素代谢物。
  • HY-101107
    Allopregnanolone >98.0%
    Allopregnanolone是孕酮代谢物。它是GABA受体的变构调节剂。
  • HY-101397
    Allopurinol riboside 99.04%
    Allopurinol riboside是别嘌呤醇的代谢物,能有效地抑制寄生虫。
  • HY-101407
    Nicotinamide N-oxide 99.45%
    Nicotinamide N-oxide是生物体内烟酰胺分解代谢物, 是高效选择性的CXCR2受体拮抗剂。
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