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RSV

Human respiratory syncytial virus (RSV) is a virus that causes respiratory tract infections. RSV is a negative-sense, single-stranded RNA virus of the family Paramyxoviridae, which includes common respiratory viruses such as those causingmeasles and mumps. RSV is a member of the paramyxovirus subfamily Pneumovirinae. RSV is a major cause of lower respiratory tract infections and hospital visits during infancy and childhood.

Human respiratory syncytial virus (8)
产品名称 目录号 简述
ALS-8112 HY-12983

ALS-8112 is a potent, selective RSV polymerase inhibitor, exhibits the most promising activity in the RSV replicon assay with an EC50 of 0.15 μM.

ALS-8176 HY-12983A

ALS-8176 is a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.

Presatovir HY-16727

Presatovir is a novel, orally bioavailable RSV fusion inhibitor, against a wide range of RSV A and B clinical isolates (mean EC50 = 0.43 nM).

Ribavirin HY-B0434

Ribavirin (利巴韦林) 是抗病毒抗代谢化合物,能阻断核苷酸合成,可作用于RNA、DNA病毒。

RSV604 HY-12993

RSV604是RSV病毒复制抑制剂,EC50值0.86uM,RSV核蛋白抑制剂。

RSV604 R enantiomer HY-12993B

RSV604 R enantiomer is the R-enantiomer of RSV604.

RSV604 racemate HY-12993A

RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.

TMC353121 HY-11097

TMC353121是RSV融合抑制剂,pEC50为9.9,在肺中的t1/2为25 h。

Tags: RSV 抑制 | RSV 蛋白 | RSV 抑制剂 | RSV FDA上市药物 | RSV 和癌症 | RSV 活性 | RSV 激活 | RSV 信号通路 | RSV 抑制剂筛选 | RSV 高通量筛选 | RSV 抑制剂临床 | RSV 抑制剂药物 | RSV 抑制剂综述 | RSV 抑制剂研发 | RSV 抑制剂供应商 | RSV 抑制剂分销商

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