2. Immunology/Inflammation
  3. Fc Receptor (FcR)
  4. Anti-Mouse CD16/CD32 Antibody (2.4G2)

Anti-Mouse CD16/CD32 Antibody (2.4G2) 

目录号: HY-P99125 纯度: ≥95.0%
COA 技术支持

Anti-Mouse CD16/CD32 Antibody (2.4G2) 是一种抗小鼠 CD16/CD32 IgG2b 单克隆抗体。Anti-Mouse CD16/CD32 Antibody (2.4G2) 可以阻断 Fcγ 受体介导的免疫反应。Anti-Mouse CD16/CD32 Antibody (2.4G2) 可以阻断 CD16 和 FcγRs 的结合，从而减少泡沫细胞的产生。Anti-Mouse CD16/CD32 Antibody (2.4G2) 可用于动脉粥样硬化和自身免疫性血液疾病的研究。

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Anti-Mouse CD16/CD32 Antibody (2.4G2) Chemical Structure

Anti-Mouse CD16/CD32 Antibody (2.4G2) Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥1200
In-stock
5 mg ￥4600
In-stock
10 mg ￥8300
In-stock
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100 mg   询价  

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Anti-Mouse CD16/CD32 Antibody (2.4G2) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD16/CD32 Antibody (2.4G2) is an anti-mouse CD16/CD32 IgG2b monoclonal antibody. Anti-Mouse CD16/CD32 Antibody (2.4G2) can block Fcγ receptor-mediated immune responses. Anti-Mouse CD16/CD32 Antibody (2.4G2) can block the combination of CD16 and FcγRs to reduce the production of foam cells. Anti-Mouse CD16/CD32 Antibody (2.4G2) can be used for research on atherosclerosis and autoimmune hematological disorders[1][2][3][4].

同型

Rat IgG2b kappa
推荐同型对照抗体
体外研究
(In Vitro)

Anti-Mouse CD16/CD32 Antibody (2.4G2) 显著抑制 MDALDL 与 J774 细胞的结合[1]。
Anti-Mouse CD16/CD32 Antibody (2.4G2) (24 小时) 通过阻断 RAW264.7 细胞中的 FcγRs 显著减少泡沫细胞的产生[1]。
Anti-Mouse CD16/CD32 Antibody (2.4G2) (0.01 mg/mL, 6 天) 抑制抗体分泌细胞 (ASC) 的形成，并降低 F8-/- 小鼠脾脏 T 细胞中的 T 细胞因子水平，如 IFN-γ, IL-10 和 TNF-α[2]。
Anti-Mouse CD16/CD32 Antibody (2.4G2) (0.01 mg/mL, 4 天) 干扰 F8-/- 小鼠脾脏 B 细胞对 FVIII 免疫复合物的摄取和呈递[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD16/CD32 Antibody (2.4G2) 相关抗体:
体内研究
(In Vivo)

Anti-Mouse CD16/CD32 Antibody (2.4G2) (8 μg/g, 静脉注射, 单次剂量, 注射 MAb 6A6 前 1 小时) 可以抑制 γ-/- 小鼠的血小板清除率[3]。
Anti-Mouse CD16/CD32 Antibody (2.4G2) (100 μg, 腹腔注射, 单次剂量, 注射 MWReg30 前 24 小时) 逆转了大鼠抗鼠血小板 MWReg30 在 NMRI 小鼠中的病理作用[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: γ-/- mice (2-4 months)[3]
Dosage: 8 μg/g
Administration: Intravenous injection (i.v.), single dose, 1 h before injection of MAb 6A6
Result: Maintained a baseline platelet count of 86%, significantly higher than the control group.
Animal Model: NMRI mice (5-7 weeks)[4]
Dosage: 100 μg
Administration: Intraperitoneal injection (i.p.), single dose, 24 h before injection of MWReg30
Result: Prevented MWReg30 induced hypothermia and acute lung injury.
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (266 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-Mouse CD16/CD32 Antibody (2.4G2) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD16/CD32 Antibody (2.4G2)Fc Receptor (FcR)Fc ReceptorCD16/CD32atherosclerosisMDALDLFcγplateletT cellInhibitorinhibitorinhibit

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