2. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. Apoptosis Reactive Oxygen Species (ROS)
  4. Antitumor agent-204

Antitumor agent-204 (compound 15a) 是一种有效的抗肿瘤药物。Antitumor agent-204 具有细胞毒性。Antitumor agent-204 诱导一氧化氮 (NO) 释放和活性氧 (reactive oxygen species) 生成。Antitumor agent-204 诱导细胞凋亡，并诱导细胞周期停滞于 G2/M 期。Antitumor agent-204 表现出抗肿瘤活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Antitumor agent-204 Chemical Structure

Antitumor agent-204 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Antitumor agent-204 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-204 (compound 15a) is a potent antitumor agent. Antitumor agent-204 shows cytotoxicity. Antitumor agent-204 induces nitric oxide (NO) release and reactive oxygen species (ROS) generation. Antitumor agent-204 induces apoptosis and induces cell cycle arrest at G2/M phase. Antitumor agent-204 shows antitumor activity[1].

体外研究
(In Vitro)

Antitumor agent-204 (compound 15a) (0-10 μM; 48 h) shows cytotosicity for A549, A549/Taxol MDA-MB-231, MCF-7, BEAS-2B, HUVEC cells with IC50s of 4.43, 0.87, 1.20, 5.54, 10.73, 13.25 μM, respectively[1].
Antitumor agent-204 (1, 2.5, 5 μM; 24 h) induces cell apoptosis in a dose-dependentmanner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-204 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: A549, A549/Taxol, MDA-MB-231, MCF-7, BEAS-2B, HUVEC cells
Concentration: 0-10 μM
Incubation Time: 48 h
Result: Showed cytotoxicity for A549, A549/Taxol MDA-MB-231, MCF-7, BEAS-2B, HUVEC cells with IC50s of 4.43, 0.87, 1.20, 5.54, 10.73, 13.25 μM, respectively.

Apoptosis Analysis[1]

Cell Line: A549/Taxol cells
Concentration: 1, 2.5, 5 μM
Incubation Time: 24 h
Result: Induced cell apoptosis in a dose-dependentmanner.
体内研究
(In Vivo)

Antitumor agent-204 (1, 5, 10 mg/kg; IP; once every 4 days for 16 days) 在小鼠中显示出抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female BALB/c nude mice (A549/Taxol cells)[1]
Dosage: 1, 5, 10 mg/kg
Administration: IP; Once every 4 days for 16 days
Result: Showed antitumor activity by significantly inhibited tumor growth by 50.2 %, 61.2 %, and 72.3 % (w/w) at 1, 5, and 10 mg/kg, respectively.
分子量

703.76

Formula

C39H33N3O8S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-204 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-204Antitumor agent204Antitumor agent 204ApoptosisReactive Oxygen Species (ROS)antitumorreactive oxygen speciesapoptosisA549/Taxol cellsG2/M phaseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Antitumor agent-204
目录号：
HY-176738
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z