1. Epigenetics GPCR/G Protein PI3K/Akt/mTOR Neuronal Signaling
  2. Cannabinoid Receptor AMPK
  3. CB1R/AMPK modulator 1

CB1R/AMPK modulator 1 (Compound 38-S)是一种口服活性的 CB1R/AMPK 调节剂,Ki 为 0.81 nM, CB1R 的 IC50 为 3.9 nM。CB1R/AMPK modulator 1 激活 AMPK。CB1R/AMPK modulator 1 减少食物摄入量和体重,并改善葡萄糖耐量和胰岛素敏感性。

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CB1R/AMPK modulator 1 Chemical Structure

CB1R/AMPK modulator 1 Chemical Structure

CAS No. : 2711012-08-5

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  • 生物活性

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生物活性

CB1R/AMPK modulator 1 (Compound 38-S) is an orally active CB1R/AMPK modulator, with an Ki of 0.81 nM and an IC50 of 3.9 nM for CB1R. CB1R/AMPK modulator 1 activates AMPK. CB1R/AMPK modulator 1 reduces food intake and body weight, and improves glucose tolerance and insulin sensitivity[1].

IC50 & Target

3.9 nM (CB1R)[1]

分子量

557.45

Formula

C25H22Cl2N6O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CB1R/AMPK modulator 1
目录号:
HY-155967
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