2. Metabolic Enzyme/Protease
  3. Prolyl Endopeptidase (PREP)
  4. CGS 24592

CGS 24592 是一种具有口服活性，选择性和有效的中性内多肽酶 24.11 (NEP) 抑制剂，IC50 值为 1.6 nmol/L。CGS 24592 减少心房钠素 (ANP) 的降解，增加血浆中 ANP 的浓度，降低血压。CGS 24592 有望用于高血压、充血性心力衰竭等心血管疾病的研究。

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CGS 24592 Chemical Structure

CGS 24592 Chemical Structure

CAS No. : 147923-04-4

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CGS 24592 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CGS 24592 is an orally active, selective and potent neutral endopeptidase 24.11 (NEP) inhibitor with an IC50 value of 1.6 nmol/L. CGS 24592 reduces the degradation of atrial natriuretic peptide (ANP), increases the concentration of ANP in the plasma, and reduces blood pressure. CGS 24592 is promising for research of cardiovascular disease, such as hypertension and congestive heart failure[1].

分子量

406.37

Formula

C19H23N2O6P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CGS 24592 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CGS 24592147923-04-4CGS24592CGS-24592Prolyl Endopeptidase (PREP)prolyl oligopeptidasePOPNEPANPhypertensioncongestive heart failureInhibitorinhibitorinhibit

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