2. Vitamin D Related/Nuclear Receptor
  3. Pregnane X Receptor (PXR)
  4. Cholic acid-Glu

Cholic acid-Glu 是 Cholic acid (HY-N0324) 的衍生物。在克罗恩病中，Cholic acid-Glu 的丰度增加。Cholic acid-Glu 可增强小肠类器官组织中 PXR 的活化，并显著增加下游 PXR 靶基因 Cyp3a11 的表达。

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Cholic acid-Glu Chemical Structure

Cholic acid-Glu Chemical Structure

CAS No. : 95051-21-1

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Cholic acid-Glu 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cholic acid-Glu is a derivative of Cholic acid (HY-N0324). The abundance of Cholic acid-Glu is increased in Crohn’s disease. Cholic acid-Glu increases PXR activation and significantly increases the expression of the downstream PXR target gene Cyp3a11 in small intestinal organoid tissue[1].

分子量

521.69

Formula

C29H47NO7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cholic acid-Glu 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Cholic acid-Glu95051-21-1Pregnane X Receptor (PXR)Pregnane X ReceptorCrohn’s diseaseCholic acid derivativeInhibitorinhibitorinhibit

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