2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. Dofequidar fumarate (Standard)

Dofequidar fumarate (Standard) 

目录号: HY-17013AR 纯度: ≥98%
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Dofequidar (fumarate) (Standard) 是 Dofequidar (fumarate) 的分析标准品。本产品用于研究及分析应用。Dofequidar fumarate (MS-209) 是一种具有口服活性喹啉化合物，可阻断 P-糖蛋白 (P-gp) 和多药耐药相关蛋白-1 (MDR-1)。Dofequidar fumarate 对多药耐药肿瘤细胞具有很强的逆转作用。Dofequidar fumarate 竞争性抑制 ABCB1/P-gp、ABCC1/M

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Dofequidar fumarate (Standard) Chemical Structure

Dofequidar fumarate (Standard) Chemical Structure

CAS No. : 153653-30-6

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生物活性

Dofequidar (fumarate) (Standard) is the analytical standard of Dofequidar (fumarate). This product is intended for research and analytical applications. Dofequidar fumarate (MS-209) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1). Dofequidar fumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect.

分子量

597.66

Formula

C34H35N3O7
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Dofequidar fumarate (Standard) 相关分类

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Keywords:

Dofequidar fumarate (Standard)153653-30-6P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

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