2. Protein Tyrosine Kinase/RTK Apoptosis
  3. FLT3 Apoptosis
  4. FLT3-IN-33

FLT3-IN-33 (Compound 7r) 是一种 FLT3 抑制剂，其 IC50 为 7.82 nM。FLT3-IN-33 对急性髓系白血病 (AML) 细胞 (例如 MV4-11 和 MOLM-13 细胞) 具有优异的抗癌活性。FLT3-IN-33 显著诱导细胞凋亡 (apoptosis) 并抑制 FLT3 通路的磷酸化。FLT3-IN-33 可用于 AML 和其他癌症的研究。

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FLT3-IN-33 Chemical Structure

FLT3-IN-33 Chemical Structure

CAS No. : 3035801-67-0

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FLT3-IN-33 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FLT3-IN-33 (Compound 7r) is a FLT3 inhibitor with an IC50 of 7.82  nM. FLT3-IN-33 has superior anticancer activities against acute myeloid leukemia (AML) cells, such as MV4-11 and MOLM-13 cells. FLT3-IN-33 significantly induces cell apoptosis and inhibits phosphorylation of FLT3 pathways. FLT3-IN-33 can be used for AML and other cancers research[1].

分子量

464.61

Formula

C25H36N8O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FLT3-IN-33 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FLT3-IN-333035801-67-0FLT3ApoptosisCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3InhibitorsAnticancerAcute Myeloid LeukemiaAMLMV4-11 cellsMOLM-13 cellsInhibitorinhibitorinhibit

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产品名称：
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目录号：
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