1. Neuronal Signaling
    Stem Cell/Wnt
  2. γ-secretase
  3. γ-Secretase modulator 4

γ-Secretase modulator 4 

目录号: HY-128581
产品使用指南

γ-Secretase modulator 4 是一种有效的 γ- 分泌酶调节剂 (γ-secretase),在人类和小鼠中降低 Aβ42 产生的 IC50 值分别为 0.014 μM 和 0.017 μM。

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γ-Secretase modulator 4 Chemical Structure

γ-Secretase modulator 4 Chemical Structure

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Description

γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively[1].

IC50 & Target

IC50: 0.014 μM (Aβ42, human), 0.017 μM (Aβ42, mouse)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

402.42

Formula

C₂₃H₁₉FN₄O₂

SMILES

N#CC1=C(OC)C2=C(C=C1)NC(C3=CN(CCO[C@H]4C5=CC=CC(F)=C5C)C4=N3)=C2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
γ-Secretase modulator 4
目录号:
HY-128581
需求量:

γ-Secretase modulator 4

Cat. No.: HY-128581