2. Gene
  3. H6pd - hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Gene

H6pd - hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gpd1; G6pd1; Gpd-1

基因 ID: 100198 | 基因类型: protein coding

关于 H6pd

功能概要

Enables 6-phosphogluconolactonase activity and glucose-6-phosphate dehydrogenase activity. Involved in regulation of cortisol biosynthetic process. Acts upstream of or within pentose-phosphate shunt. Located in sarcoplasmic reticulum. Is expressed in alimentary system; cranium; facial bone primordium; liver; and tooth. Human ortholog(s) of this gene implicated in cortisone reductase deficiency; cortisone reductase deficiency 1; and multiple sclerosis. Orthologous to human H6PD (hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

H6pd 基因产物(2)

mRNA Protein Name
NM_001291004.1 NP_001277933.1 GDH/6PGL endoplasmic bifunctional protein isoform 2 precursor
NM_173371.4 NP_775547.2 GDH/6PGL endoplasmic bifunctional protein isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 6-phosphogluconolactonase activity IDA
IDA: 通过直接分析推断
12831846 MGI
enables glucose-6-phosphate dehydrogenase activity IDA
IDA: 通过直接分析推断
12831846 MGI
enables glucose-6-phosphate dehydrogenase activity IMP
IMP: 通过突变表型推断
18222920 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within pentose-phosphate shunt IDA
IDA: 通过直接分析推断
12831846 MGI
involved in regulation of cortisol biosynthetic process IMP
IMP: 通过突变表型推断
16356929 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in endoplasmic reticulum IMP
IMP: 通过突变表型推断
18222920 MGI
is active in sarcoplasmic reticulum IMP
IMP: 通过突变表型推断
18222920 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

GDH/6PGL endoplasmic bifunctional protein

glucose 1-dehydrogenase

glucose-6-phosphate dehydrogenase 1

相关产品

Approval
生物活性分子 (7)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10617A Rucaparib Inhibitor 99.97% 否
HY-10617 Rucaparib phosphate Inhibitor 99.76% 是
HY-102003 Rucaparib (monocamsylate) Inhibitor 99.91% 是
HY-102003A Rucaparib camsylate Inhibitor / 否
HY-10617C Rucaparib tartrate Inhibitor / 否
HY-10617B Rucaparib hydrochloride Inhibitor / 否
HY-10617D Rucaparib acetate Inhibitor / 否
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05980 H6PD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-10617AS Rucaparib-d8 Inhibitor / 否
HY-RS17126 H6pd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23571 H6pd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens H6pd NCBI NCBI:9563
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