2. Gene
  3. Cyp11b1 - cytochrome P450, family 11, subfamily b, polypeptide 1 Gene

Cyp11b1 - cytochrome P450, family 11, subfamily b, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FHI; CPN1; Cyp11b; Cyp11b-1

基因 ID: 110115 | 基因类型: protein coding

关于 Cyp11b1

功能概要

Enables corticosterone 18-monooxygenase activity. Acts upstream of or within glucocorticoid biosynthetic process. Located in mitochondrion. Is expressed in adrenal gland; gland; lung; and testis. Used to study congenital adrenal hyperplasia. Human ortholog(s) of this gene implicated in several diseases, including congenital adrenal hyperplasia; corticosterone methyloxidase deficiency 1; diabetes mellitus (multiple); hypertension (multiple); and primary hyperaldosteronism (multiple). Orthologous to human CYP11B1 (Cytochrome P450 family 11 subfamily B member 1) and CYP11B2 (Cytochrome P450 family 11 subfamily B member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp11b1 基因产物(1)

mRNA Protein Name
NM_001033229.3 NP_001028401.2 cytochrome P450, family 11, subfamily b, polypeptide 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables corticosterone 18-monooxygenase activity IDA
IDA: 通过直接分析推断
1686470 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucocorticoid biosynthetic process IDA
IDA: 通过直接分析推断
1686470 MGI
acts upstream of or within glucocorticoid biosynthetic process IMP
IMP: 通过突变表型推断
10224232 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
10224232 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytochrome P450, family 11, subfamily b, polypeptide 1

steroid-11-beta-hydroxylase

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-16276 Osilodrostat Inhibitor 99.90% 是
HY-16276A Osilodrostat phosphate Inhibitor 99.35% 是
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135794 11-Ketodihydrotestosterone Agonist 98.03% 否
HY-101217 BI 689648 Inhibitor 99.20% 否
HY-135281 CYP11B2-IN-1 Inhibitor 99.83% 否
HY-151140 CYP11B1-IN-2 Inhibitor / 否
HY-176480 CYP11B2-IN-3 Inhibitor / 否
HY-RS03435 CYP11B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-163751 STING-IN-9 Inhibitor / 否
HY-RS17315 Cyp11b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23770 Cyp11b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp11b1 NCBI NCBI:1584
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z