1. Gene
  2. Map2k6 - mitogen-activated protein kinase kinase 6 Gene

Map2k6 - mitogen-activated protein kinase kinase 6 Gene

种属: Rattus norvegicus

同用名: Mkk6

基因 ID: 114495 | 基因类型: protein coding

关于 Map2k6

功能概要

Enables MAP kinase kinase activity. Involved in several processes, including cellular response to sorbitol; positive regulation of macromolecule metabolic process; and response to ischemia. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Pick's disease; cervical cancer; ovarian carcinoma; progressive supranuclear palsy; and restrictive cardiomyopathy. Orthologous to human MAP2K6 (mitogen-activated protein kinase kinase 6). [provided by Alliance of Genome Resources, Apr 2022]

Map2k6 基因产物(1)

mRNA Protein Name
NM_053703.3 NP_446155.1 dual specificity mitogen-activated protein kinase kinase 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables MAP kinase kinase activity IDA
IDA: 通过直接分析推断
20550965 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to sorbitol IEP
IEP: 通过表达模式推断
20550965 RGD
involved in ovulation cycle process IEP
IEP: 通过表达模式推断
11328854 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
12029621 RGD
involved in positive regulation of nitric-oxide synthase biosynthetic process IMP
IMP: 通过突变表型推断
10593906 RGD
involved in positive regulation of prostaglandin secretion IMP
IMP: 通过突变表型推断
12649265 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
20550965 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
20550965 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16755153 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dual specificity mitogen-activated protein kinase kinase 6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2k6 NCBI NCBI:5608