2. Gene
  3. LYPD1 - LY6/PLAUR domain containing 1 Gene

LYPD1 - LY6/PLAUR domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 LY6/PLAUR 域 1

种属: Homo sapiens

同用名: PHTS; LYPDC1

基因 ID: 116372 | 基因类型: protein coding

关于 LYPD1

Cytogenetic location: 2q21.2 Genomic coordinates (GRCh38): 2:132,643,286-132,671,526 (from NCBI)

This gene has 3 transcripts (splice variants), 249 orthologues and 3 paralogues. Broad expression in brain (RPKM 4.3), colon (RPKM 1.3) and 16 other tissues.

功能概要

预测具有乙酰胆碱受体结合活性和乙酰胆碱受体抑制剂活性。预测参与乙酰胆碱受体信号通路。预计在几个过程的上游或内部起作用，包括行为恐惧反应；胆碱能突触传递；和蛋白质定位到质膜的负调节。预测位于膜中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to act upstream of or within several processes, including behavioral fear response; cholinergic synaptic transmission; and negative regulation of protein localization to plasma membrane. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

LYPD1 基因产物(4)

mRNA Protein Name
NM_001077427.4 NP_001070895.1 ly6/PLAUR domain-containing protein 1 isoform b
NM_001321234.2 NP_001308163.1 ly6/PLAUR domain-containing protein 1 isoform c
NM_001321235.2 NP_001308164.1 ly6/PLAUR domain-containing protein 1 isoform b
NM_144586.7 NP_653187.3 ly6/PLAUR domain-containing protein 1 isoform a precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ly6/PLAUR domain-containing protein 1

putative HeLa tumor suppressor

关联疾病

疾病名称 别名
Arthrogryposis, Distal, Type 2a

Freeman-Sheldon Syndrome

Craniocarpotarsal Dystrophy

Craniocarpotarsal Dysplasia

DA2A

Whistling Face-Windmill Vane Hand Syndrome

Fss

Distal Arthrogryposis Type 2a

Whistling Face Syndrome

Freeman-Burian Syndrome

Arthrogryposis Distal Type 2a

Distal Arthrogryposis, Type 2a

Fbs

Arthrogryposis, Distal, 2a
Melanotic Medulloblastoma

Medulloblastoma, Melanotic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07915 LYPD1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LYPD1 RGD RGD:1549754
Macaca mulatta LYPD1 VGNC VGNC:104542
Felis catus LYPD1 VGNC VGNC:63339
Mus musculus LYPD1 MGD MGI:1919835
Canis familiaris LYPD1 VGNC VGNC:42883
Bos taurus LYPD1 VGNC VGNC:31099
Others LYPD1 NCBI
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