2. Gene
  3. Rims2 - regulating synaptic membrane exocytosis 2 Gene

Rims2 - regulating synaptic membrane exocytosis 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RIM2; Serg2; Rab3ip2; Syt3-rs; Rim2(+4A); mKIAA0751; Rim2(+40A); Rim2(+44A); 2810036I15Rik

基因 ID: 116838 | 基因类型: protein coding

关于 Rims2

功能概要

Enables transmembrane transporter binding activity. A structural constituent of presynaptic active zone. Involved in neurotransmitter secretion; positive regulation of gene expression; and regulation of nervous system process. Acts upstream of or within several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of exocytosis; and signal release. Located in GABA-ergic synapse and inhibitory synapse. Is active in glutamatergic synapse. Is expressed in testis. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2). [provided by Alliance of Genome Resources, Apr 2022]

Rims2 基因产物(4)

mRNA Protein Name
NM_001256382.1 NP_001243311.1 regulating synaptic membrane exocytosis protein 2 isoform a
NM_001256383.1 NP_001243312.1 regulating synaptic membrane exocytosis protein 2 isoform b
NM_001256384.1 NP_001243313.1 regulating synaptic membrane exocytosis protein 2 isoform d
NM_053271.2 NP_444501.1 regulating synaptic membrane exocytosis protein 2 isoform c
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11056535 MGI
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
11056535 MGI
enables structural constituent of presynaptic active zone IDA
IDA: 通过直接分析推断
21241895 MGI
enables structural constituent of presynaptic active zone IEP
IEP: 通过表达模式推断
27537483 MGI
enables structural constituent of presynaptic active zone IMP
IMP: 通过突变表型推断
21241895 MGI
enables transmembrane transporter binding IDA
IDA: 通过直接分析推断
20452978 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11598134 MGI
acts upstream of or within calcium ion-regulated exocytosis of neurotransmitter IGI
IGI: 通过遗传相互作用推断
17124501 MGI
acts upstream of or within calcium-ion regulated exocytosis IDA
IDA: 通过直接分析推断
11056535 MGI
involved in establishment of localization in cell IMP
IMP: 通过突变表型推断
11598134 MGI
acts upstream of or within insulin secretion IDA
IDA: 通过直接分析推断
11598134 MGI
involved in insulin secretion IMP
IMP: 通过突变表型推断
11598134 MGI
acts upstream of or within neurotransmitter secretion IGI
IGI: 通过遗传相互作用推断
25730884 MGI
involved in positive regulation of excitatory postsynaptic potential IGI
IGI: 通过遗传相互作用推断
21262469 MGI
involved in positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
21262469 MGI
involved in positive regulation of inhibitory postsynaptic potential IGI
IGI: 通过遗传相互作用推断
21262469 MGI
involved in regulation of calcium-dependent activation of synaptic vesicle fusion IDA
IDA: 通过直接分析推断
21241895 MGI
involved in regulation of calcium-dependent activation of synaptic vesicle fusion IMP
IMP: 通过突变表型推断
21241895 MGI
acts upstream of or within regulation of exocytosis IMP
IMP: 通过突变表型推断
20674857 MGI
acts upstream of or within regulation of membrane potential IDA
IDA: 通过直接分析推断
20452978 MGI
involved in spontaneous neurotransmitter secretion IGI
IGI: 通过遗传相互作用推断
21262469 MGI
involved in synaptic vesicle docking IDA
IDA: 通过直接分析推断
21241895 MGI
involved in synaptic vesicle docking IMP
IMP: 通过突变表型推断
21241895 MGI
involved in synaptic vesicle priming IDA
IDA: 通过直接分析推断
21262469 MGI
involved in synaptic vesicle priming IMP
IMP: 通过突变表型推断
21262469 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
21262469 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
21262469 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21241895 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
21241895 MGI
located in inhibitory synapse IMP
IMP: 通过突变表型推断
22753485 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

regulating synaptic membrane exocytosis protein 2

RIM 2

Rab3 interacting protein 1

Rab3 interacting protein 2

rab-3-interacting protein 2

rab3-interacting protein 2

synaptic exocytosis regulator 2

synaptotagmin 3, related sequence

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11979 RIMS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21733 Rims2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rims2 NCBI NCBI:9699
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