2. Gene
  3. ACAP3 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Gene

ACAP3 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：具有卷曲螺旋、锚蛋白重复序列和 PH 结构域的 ArfGAP 3

种属: Homo sapiens

同用名: CENTB5

基因 ID: 116983 | 基因类型: protein coding

关于 ACAP3

This gene has 13 transcripts (splice variants), 274 orthologues and 28 paralogues. Ubiquitous expression in skin (RPKM 16.2), brain (RPKM 12.8) and 24 other tissues.

功能概要

预测启用 GTPase 激活剂活性和金属离子结合活性。预计参与催化活性的调节。预计在神经元迁移和神经元投射发育调节的上游或内部起作用。预计位于生长锥内。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in regulation of catalytic activity. Predicted to act upstream of or within neuron migration and regulation of neuron projection development. Predicted to be located in growth cone. [provided by Alliance of Genome Resources, Apr 2022]

ACAP3 基因产物(1)

mRNA Protein Name
NM_030649.3 NP_085152.2 arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
33961781 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACAP3 蛋白结构

PH

PH: PH domain (269 - 362)

ArfGap

ArfGap: Putative GTPase activating protein for Arf (404 - 520)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (673 - 764)

  • 0
  • 200
  • 400
  • 600
  • 834 a.a.
蛋白主名 其他名称

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

centaurin-beta-5

ACAP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ACAP3 Q96P50 ACAP2 Homo sapiens Q15057
Anti Tag CoIP
35271311
种属内
ACAP3 Q96P50 ACAP2 Homo sapiens Q15057
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Osteosclerotic Myeloma
Brachial Plexus Neuritis

Brachial Neuritis

Parsonage-Aldren-Turner Syndrome
Recessive Dystrophic Epidermolysis Bullosa

Autosomal Recessive Dystrophic Epidermolysis Bullosa Generalisata Gravis

Autosomal Recessive Dystrophic Epidermolysis Bullosa, Hallopeau-Siemens Type

Rdeb, Hallopeau-Siemens Type

Severe Generalized Rdeb

Severe Generalized Recessive Dystrophic Epidermolysis Bullosa

Rdeb Generalisata Gravis

Rdeb, Severe Generalized

Rdeb-Sev Gen

Recessive Dystrophic Epidermolysis Bullosa, Severe Generalized

Hallopeau-Siemens Disease
Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00135 ACAP3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ACAP3 VGNC VGNC:59499
Canis familiaris ACAP3 VGNC VGNC:37497
Bos taurus ACAP3 VGNC VGNC:25528
Mus musculus ACAP3 MGD MGI:2153589
Rattus norvegicus ACAP3 RGD RGD:1310711
Macaca mulatta ACAP3 VGNC VGNC:69434
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z