2. Gene
  3. Atp7b - ATPase, Cu++ transporting, beta polypeptide Gene

Atp7b - ATPase, Cu++ transporting, beta polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: tx; WND; Atp7a

基因 ID: 11979 | 基因类型: protein coding

关于 Atp7b

功能概要

Enables P-type divalent copper transporter activity. Acts upstream of or within several processes, including cellular transition metal ion homeostasis; lactation; and protein maturation by copper ion transfer. Located in membrane and trans-Golgi network. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Wilson disease. Human ortholog(s) of this gene implicated in Wilson disease. Orthologous to human ATP7B (ATPase copper transporting beta). [provided by Alliance of Genome Resources, Apr 2022]

Atp7b 基因产物(2)

mRNA Protein Name
NM_001403709.1 NP_001390638.1 copper-transporting ATPase 2 isoform 1
NM_007511.3 NP_031537.2 copper-transporting ATPase 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables P-type divalent copper transporter activity IDA
IDA: 通过直接分析推断
11237756 MGI
enables P-type divalent copper transporter activity IMP
IMP: 通过突变表型推断
11237756 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within copper ion transport IDA
IDA: 通过直接分析推断
11237756 MGI
acts upstream of or within copper ion transport IMP
IMP: 通过突变表型推断
11085952 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
11085952 MGI
acts upstream of or within intracellular copper ion homeostasis IMP
IMP: 通过突变表型推断
1588441 MGI
acts upstream of or within intracellular zinc ion homeostasis IMP
IMP: 通过突变表型推断
8040371 MGI
acts upstream of or within lactation IMP
IMP: 通过突变表型推断
1588441 MGI
acts upstream of or within protein maturation by copper ion transfer IMP
IMP: 通过突变表型推断
16436657 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
10441329 MGI
located in trans-Golgi network IDA
IDA: 通过直接分析推断
11085952 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

copper-transporting ATPase 2

Wilson protein

copper pump 2

toxic milk

wilson disease-associated protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01236 ATP7B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17601 Atp7b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24061 Atp7b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp7b NCBI NCBI:540
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