1. Gene
  2. Capn2 - calpain 2 Gene

Capn2 - calpain 2 Gene

种属: Mus musculus

同用名: Capa2; CALP80; Capa-2; m-calpin; m-calpain

基因 ID: 12334 | 基因类型: protein coding

关于 Capn2

功能概要

Enables calcium-dependent cysteine-type endopeptidase activity. Involved in cellular response to amino acid stimulus and proteolysis. Acts upstream of or within blastocyst development and myoblast fusion. Located in several cellular components, including chromatin; cytosol; and lysosome. Is expressed in several structures, including hindbrain; lens epithelium; oral region epithelium; skin; and spinal cord floor plate. Orthologous to human CAPN2 (calpain 2). [provided by Alliance of Genome Resources, Apr 2022]

Capn2 基因产物(1)

mRNA Protein Name
NM_009794.4 NP_033924.2 calpain-2 catalytic subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium-dependent cysteine-type endopeptidase activity IDA
IDA: 通过直接分析推断
22555453 MGI
enables peptidase activity IDA
IDA: 通过直接分析推断
21849499 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst development IMP
IMP: 通过突变表型推断
16433929 MGI
involved in cellular response to amino acid stimulus IDA
IDA: 通过直接分析推断
22711986 MGI
acts upstream of or within myoblast fusion IMP
IMP: 通过突变表型推断
10949052 MGI
involved in protein catabolic process at postsynapse EXP
EXP: 通过实验结果推断
20089917 MGI
involved in protein catabolic process at postsynapse IDA
IDA: 通过直接分析推断
20089917 MGI
involved in protein catabolic process at postsynapse IEP
IEP: 通过表达模式推断
20089917 MGI
involved in protein catabolic process at postsynapse IMP
IMP: 通过突变表型推断
20089917 MGI
involved in proteolysis IDA
IDA: 通过直接分析推断
22711986 MGI
involved in synaptic vesicle endocytosis EXP
EXP: 通过实验结果推断
35318705 MGI
involved in synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
35318705 MGI
involved in synaptic vesicle endocytosis IEP
IEP: 通过表达模式推断
35318705 MGI
involved in synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
35318705 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
18415939 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
18415939 MGI
located in cytosol IDA
IDA: 通过直接分析推断
22555453 MGI
located in lysosome IDA
IDA: 通过直接分析推断
22555453 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18415939 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
20089917 MGI
is active in postsynapse IMP
IMP: 通过突变表型推断
20089917 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calpain-2 catalytic subunit

80 kDa M-calpain subunit

CANP 2

calcium-activated neutral proteinase 2

calpain M-type

calpain-2 large subunit

cysteine proteinase

m-calpain 80 kDa large subunit

m-calpain large subunit

millimolar-calpain

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Capn2 NCBI NCBI:824