1. Gene
  2. Cbx2 - chromobox 2 Gene

Cbx2 - chromobox 2 Gene

种属: Mus musculus

同用名: pc; M33; MOD2

基因 ID: 12416 | 基因类型: protein coding

关于 Cbx2

功能概要

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in results in male-to-female gonadal sex reversal. [provided by RefSeq, Sep 2015]

Cbx2 基因产物(1)

mRNA Protein Name
NM_007623.3 NP_031649.2 chromobox protein homolog 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
16687444 MGI
enables methylated histone binding IDA
IDA: 通过直接分析推断
16537902 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9367786 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9312051 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of PcG protein complex IDA
IDA: 通过直接分析推断
9312051 MGI
located in euchromatin IDA
IDA: 通过直接分析推断
18311137 MGI
located in heterochromatin IDA
IDA: 通过直接分析推断
16537902 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16537902 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

chromobox protein homolog 2

M33 polycomb-like protein

chromobox homolog 2

modifier 3 protein

polycomb

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbx2 NCBI NCBI:84733