1. Gene
  2. PUSL1 - pseudouridine synthase like 1 Gene

PUSL1 - pseudouridine synthase like 1 Gene

中文名称:假尿苷合酶 1

种属: Homo sapiens

基因 ID: 126789 | 基因类型: protein coding

关于 PUSL1

This gene has 5 transcripts (splice variants), 182 orthologues and 2 paralogues. Ubiquitous expression in skin (RPKM 3.5), testis (RPKM 3.1) and 25 other tissues.

功能概要

预测启用假尿苷合酶活性。预计参与 tRNA 假尿苷合成。位于线粒体中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

PUSL1 基因产物(2)

mRNA Protein Name
NM_001346116.2 NP_001333045.1 tRNA pseudouridine synthase-like 1 isoform 1
NM_153339.3 NP_699170.1 tRNA pseudouridine synthase-like 1 isoform 2
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
28082677 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PUSL1 蛋白结构

PseudoU_synth_1

PseudoU_synth_1: tRNA pseudouridine synthase (18 - 123)

PseudoU_synth_1

PseudoU_synth_1: tRNA pseudouridine synthase (168 - 284)

  • 0
  • 100
  • 200
  • 303 a.a.
蛋白主名 其他名称

tRNA pseudouridine synthase-like 1

pseudouridylate synthase like 1

关联疾病

疾病名称 别名
Myopathy, Lactic Acidosis, And Sideroblastic Anemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PUSL1 VGNC VGNC:81515
Bos taurus PUSL1 VGNC VGNC:33578
Mus musculus PUSL1 MGD MGI:3047787
Canis familiaris PUSL1 VGNC VGNC:49842
Felis catus PUSL1 VGNC VGNC:80332
Rattus norvegicus PUSL1 RGD RGD:1559560