2. Gene
  3. Fn1 - fibronectin 1 Gene

Fn1 - fibronectin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fn; Fn-1; E330027I09

基因 ID: 14268 | 基因类型: protein coding

关于 Fn1

功能概要

Enables peptidase activator activity. Acts upstream of or within several processes, including calcium-independent cell-matrix adhesion; cell-substrate junction assembly; and positive regulation of axon extension. Located in apical plasma membrane and basement membrane. Is expressed in several structures, including alimentary system; cardiovascular system; egg cylinder; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1). [provided by Alliance of Genome Resources, Apr 2022]

Fn1 基因产物(7)

mRNA Protein Name
NM_001276408.1 NP_001263337.1 fibronectin isoform b precursor
NM_001276409.1 NP_001263338.1 fibronectin isoform c precursor
NM_001276410.1 NP_001263339.1 fibronectin isoform d precursor
NM_001276411.1 NP_001263340.1 fibronectin isoform e precursor
NM_001276412.1 NP_001263341.1 fibronectin isoform f precursor
NM_001276413.1 NP_001263342.1 fibronectin isoform g precursor
NM_010233.2 NP_034363.1 fibronectin isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activator activity IDA
IDA: 通过直接分析推断
16061471 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables receptor ligand activity IDA
IDA: 通过直接分析推断
36812915 MGI
enables signaling receptor binding IDA
IDA: 通过直接分析推断
34089617 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium-independent cell-matrix adhesion IDA
IDA: 通过直接分析推断
19651211 MGI
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
9441684 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
15728191 MGI
acts upstream of or within cell-substrate junction assembly IDA
IDA: 通过直接分析推断
12867986 MGI
involved in negative regulation of monocyte activation IDA
IDA: 通过直接分析推断
34089617 MGI
acts upstream of or within positive regulation of axon extension IDA
IDA: 通过直接分析推断
12879062 MGI
involved in response to muscle activity IDA
IDA: 通过直接分析推断
36812915 MGI
acts upstream of or within wound healing IMP
IMP: 通过突变表型推断
12847088 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
10742111 MGI
located in basement membrane IDA
IDA: 通过直接分析推断
8984825 MGI
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
34368841 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
2209468 MGI
is active in extracellular space IDA
IDA: 通过直接分析推断
36812915 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fibronectin

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138657 NCGC00378430 Inhibitor 99.58% 否
HY-RS05013 FN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16767 Fn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23207 Fn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fn1 NCBI NCBI:2335
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