2. Gene
  3. ZNF582 - zinc finger protein 582 Gene

ZNF582 - zinc finger protein 582 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 582

种属: Homo sapiens

基因 ID: 147948 | 基因类型: protein coding

关于 ZNF582

Cytogenetic location: 19q13.43 Genomic coordinates (GRCh38): 19:56,382,751-56,393,534 (from NCBI)

This gene has 6 transcripts (splice variants), 148 orthologues and 62 paralogues. Ubiquitous expression in thyroid (RPKM 2.0), testis (RPKM 2.0) and 25 other tissues.

功能概要

由该基因编码的蛋白质是一种 zing finger 蛋白和推定的转录因子，在宫颈癌中高度甲基化。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2016 年 2 月]

The protein encoded by this gene is a zing finger protein and putative transcription factor that is highly methylated in cervical cancers. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

ZNF582 基因产物(2)

mRNA Protein Name
NM_001320371.4 NP_001307300.2 zinc finger protein 582
NM_144690.3 NP_653291.1 zinc finger protein 582
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF582 蛋白结构

KRAB

KRAB: KRAB box (8 - 46)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (188 - 210)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (216 - 237)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (244 - 266)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (271 - 293)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (297 - 322)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (328 - 349)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (354 - 376)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (382 - 406)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (409 - 434)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 517 a.a.
蛋白主名 其他名称

zinc finger protein 582

ZNF582 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ZNF582 Q96NG8 NECTIN4 Homo sapiens Q96NY8
Anti Tag CoIP
33961781
种属内
ZNF582 Q96NG8 NECTIN4 Homo sapiens Q96NY8
Anti Tag CoIP
28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Anal Squamous Cell Carcinoma

Epidermoid Anal Carcinoma

Carcinoma Of Anal Margin
Chronic Cervicitis
Vulva Cancer

Vulvar Carcinoma

Malignant Neoplasm Of Vulva

Vulva Carcinoma

Carcinoma Of Vulva

Vulvar Cancer

Vulval Cancer

Vulvar Neoplasms

Ca Vulva

Malignant Tumor Of Vulva

Malignant Vulvar Tumor

Neoplasm Of Vulva

Vulval Neoplasm

Vulvar Neoplasm

Vulvar Tumor

Cancer Of Vulva

Malignant Tumour Of Vulva
Uterus Carcinoma In Situ
Cervix Uteri Carcinoma In Situ

Carcinoma In Situ Of Cervix

Carcinoma In Situ Of Uterine Cervix

Cervical Intraepithelial Neoplasia

Carcinoma Of Cervix Stage 0

Cervical Intraepithelial Neoplasia Grade Iii With Severe Dysplasia

Cervix Ca In Situ

Cin Iii

Cin Iii - Carcinoma In Situ Of Cervix

Cin Iii - Severe Dyskaryosis

Severe Dysplasia Of Cervix

Severe Dysplasia Of The Cervix Uteri

Squamous Intraepithelial Neoplasia, Grade Iii

Cervix Intraepithelial Neoplasia Grade 3 Ajcc V7
Vulva Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Vulva

Vulvar Squamous Cell Carcinoma

Vulvar Epidermoid Carcinoma

Squamous Cell Carcinoma Of The Vulva
Anus Cancer

Anal Cancer

Anal Carcinoma

Malignant Anal Tumor

Cancer Of The Anus

Malignant Neoplasm Of Anus

Anus Neoplasms
Cervicitis

Uterine Cervicitis

Inflammation Of Cervix
Anus Disease

Anal Fissure

Ulcer Of Anus

Anus Diseases

Anal Disease

Anal Fissure And Fistula

Anal Ulcer

Fissure In Ano

Nontraumatic Tear Of Anus

Solitary Anal Ulcer

Abnormality Of The Anus

Anal Disorders

Ulcer Of Anus And Rectum

Solitary Ulcer Of Anus

Stercoral Ulcer Of Anus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16154 ZNF582 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF582 RGD RGD:7617005
Mus musculus ZNF582 MGD MGI:3782026
Macaca mulatta ZNF582 VGNC VGNC:79608
Canis familiaris ZNF582 VGNC VGNC:48766
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