1. Gene
  2. ZNF385B - zinc finger protein 385B Gene

ZNF385B - zinc finger protein 385B Gene

中文名称:锌指蛋白 385B

种属: Homo sapiens

同用名: ZNF533

基因 ID: 151126 | 基因类型: protein coding

关于 ZNF385B

Cytogenetic location: 2q31.2-q31.3 Genomic coordinates (GRCh38): 2:179,441,982-179,861,612 (from NCBI)

This gene has 13 transcripts (splice variants), 225 orthologues and 9 paralogues. Broad expression in lung (RPKM 1.7), heart (RPKM 1.4) and 14 other tissues.

功能概要

启用 p53 绑定活动。通过 p53 类介质参与内在凋亡信号通路。位于核内。 [由基因组资源联盟提供,2022 年 4 月]

Enables p53 binding activity. Involved in intrinsic apoptotic signaling pathway by p53 class mediator. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF385B 基因产物(14)

mRNA Protein Name
NM_001113397.2 NP_001106868.1 zinc finger protein 385B isoform 2
NM_001113398.3 NP_001106869.1 zinc finger protein 385B isoform 3
NM_001282725.3 NP_001269654.1 zinc finger protein 385B isoform 3
NM_001352808.2 NP_001339737.1 zinc finger protein 385B isoform 1
NM_001352809.2 NP_001339738.1 zinc finger protein 385B isoform 4
NM_001352810.2 NP_001339739.1 zinc finger protein 385B isoform 5
NM_001352811.2 NP_001339740.1 zinc finger protein 385B isoform 6
NM_001352812.2 NP_001339741.1 zinc finger protein 385B isoform 7
NM_001352813.2 NP_001339742.1 zinc finger protein 385B isoform 3
NM_001352814.2 NP_001339743.1 zinc finger protein 385B isoform 3
NM_001352815.1 NP_001339744.1 zinc finger protein 385B isoform 3
NM_001352816.2 NP_001339745.1 zinc finger protein 385B isoform 8
NM_001352817.1 NP_001339746.1 zinc finger protein 385B isoform 9
NM_152520.6 NP_689733.4 zinc finger protein 385B isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables p53 binding IPI
IPI: 通过物理相互作用推断
22945289 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intrinsic apoptotic signaling pathway by p53 class mediator IDA
IDA: 通过直接分析推断
22945289 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
22945289 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ZNF385B 蛋白结构

zf-met

zf-met: Zinc-finger of C2H2 type (35 - 58)

zf-met

zf-met: Zinc-finger of C2H2 type (158 - 181)

zf-met

zf-met: Zinc-finger of C2H2 type (285 - 309)

zf-met

zf-met: Zinc-finger of C2H2 type (348 - 372)

  • 0
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  • 200
  • 300
  • 400
  • 471 a.a.
蛋白主名 其他名称

zinc finger protein 385B

zinc finger protein 533

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF385B RGD RGD:1311181
Bos taurus ZNF385B VGNC VGNC:37264
Canis familiaris ZNF385B VGNC VGNC:48715
Mus musculus ZNF385B MGD MGI:2444734
Felis catus ZNF385B VGNC VGNC:67301
Macaca mulatta ZNF385B VGNC VGNC:79600