1. Gene
  2. Hcfc1 - host cell factor C1 Gene

Hcfc1 - host cell factor C1 Gene

种属: Mus musculus

同用名: HCF; HCF1

基因 ID: 15161 | 基因类型: protein coding

关于 Hcfc1

功能概要

This gene encodes a transcription cofactor that regulates the progression of cell cycle and maintain the ability of embryonic stem cells to self-renew. The encoded protein is a large precursor that undergoes site-specific proteolytic cleavage to yield N- and C-terminal chains that form a non-covalent heterodimer. The encoded protein has been implicated in the regulation of expression of immediate early genes after herpes simplex virus Infection and glucose-stimulated secretion of Insulin by pancreatic beta cells. [provided by RefSeq, Aug 2015]

Hcfc1 基因产物(2)

mRNA Protein Name
NM_001411234.1 NP_001398163.1 host cell factor 1 isoform 1
NM_008224.5 NP_032250.2 host cell factor 1 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18836447 MGI
enables chromatin DNA binding IDA
IDA: 通过直接分析推断
22878500 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22878500 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
involved in release from viral latency IDA
IDA: 通过直接分析推断
9990006 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
9990006 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9990006 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

host cell factor 1

VP16 accessory protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcfc1 NCBI NCBI:3054