Hnrnpa1 - heterogeneous nuclear ribonucleoprotein A1 Gene

种属: Mus musculus

同用名: Hdp; HDP-1; Hnrpa1; hnRNP A1; hnrnp-A1

关于 Hnrnpa1

功能概要

Predicted to enable identical protein binding activity; nucleic acid binding activity; and protein domain specific binding activity. Acts upstream of or within alternative mRNA splicing, via spliceosome. Located in nucleus. Is expressed in 1-cell stage embryo; central nervous system; sensory organ; thymus; and tooth. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to human HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) and HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2). [provided by Alliance of Genome Resources, Apr 2022]